Bamaprasad Dutta

About

I am an Associate Professor in the Department of Pharmaceutical Sciences at Kumaun University, Bhimtal (Nainital), Uttarakhand, India, with research interests in molecular pharmacology, peptide drug discovery, and translational therapeutics. My research aims to bridge fundamental pharmacological research with therapeutic innovation by identifying and developing novel bioactive molecules for the treatment of age-related diseases, including diabetes and associated complications.

Our research group focuses on the discovery and development of bioactive peptides as next-generation therapeutics, with a particular emphasis on diabetes and diabetes-associated cardiovascular complications. We employ multidisciplinary approaches that integrate molecular pharmacology, multi-omics technologies (proteomics and transcriptomics), peptide chemistry, and advanced in vitro and in vivo disease models to elucidate disease mechanisms, identify and validate novel therapeutic peptides, and facilitate their translation into clinically relevant drug candidates.

My research also encompasses peptide synthesis and characterization, pharmacological evaluation, and mechanism-of-action studies to advance peptide-based therapeutics from discovery to preclinical development. Current projects are directed toward the development of orally active peptide therapeutics with improved efficacy, stability, and bioavailability, addressing the limitations of conventional peptide drugs. Through collaborative and interdisciplinary research, my laboratory strives to develop innovative therapeutic strategies for diabetes, cardiovascular diseases, and other metabolic disorders, while contributing to the advancement of precision medicine and translational pharmacology.

Employment

• Kumuan University Associate Professor
  2026 - Present
• The Neotia University Associate Professor , Head of Pharmacology
  2024 - 2026
• Nanyang Technological University Research Fellow
  2013 - 2024

Education

• Nanyang Technological University PhD
  2009 - 2013
• Jadavpur University M. Pharm
  2007 - 2009
• Jadavpur University B. Pharm
  2003 - 2007

Projects & Funding

Projects & funding information is unavailable.

Publications (28)

• Targeted Protein Degrader from Ginkgo to Mitigate Amyloid β-Induced Neurotoxicity
  Biochemistry 2026 DOI: 10.1021/acs.biochem.5c00763
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• Cell-Permeable Microprotein from Panax Ginseng Protects Against Doxorubicin-Induced Oxidative Stress and Cardiotoxicity
  Antioxidants 2025 DOI: 10.3390/antiox14040493
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• Cell-Permeable Microprotein from Panax Ginseng Protects Against Doxorubicin-Induced Oxidative Stress and Cardiotoxicity
  2025 DOI: 10.20944/preprints202503.1675.v1
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• Broad-spectrum ginsentides are principal bioactives in unraveling the cure-all effects of ginseng
  Acta Pharmaceutica Sinica B 2024 DOI: 10.1016/j.apsb.2023.10.022
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• Plant-derived cell-penetrating microprotein α-astratide aM1 targets Akt signaling and alleviates insulin resistance
  Cellular and Molecular Life Sciences 2023 DOI: 10.1007/s00018-023-04937-y
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• Decoding the Cure-all Effects of Ginseng
  2023 DOI: 10.1101/2023.04.05.535784
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• Ginsentide TP1 Protects Hypoxia-Induced Dysfunction and ER Stress-Linked Apoptosis
  2023 DOI: 10.1101/2023.04.12.536670
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• Exploring Extracellular Vesicles Biogenesis in Hypothalamic Cells through a Heavy Isotope Pulse/Trace Proteomic Approach.
  Cells 2020 DOI: 10.3390/cells9051320
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• Quantitative Proteomic Analysis of Simian Primary Hepatocytes Reveals Candidate Molecular Markers for Permissiveness to Relapsing Malaria Plasmodium cynomolgi.
  Proteomics 2019 DOI: 10.1002/pmic.201900021
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• LIR Motif-Containing Hyperdisulfide β-Ginkgotide is Cytoprotective, Adaptogenic, and Scaffold-Ready.
  Molecules (Basel, Switzerland) 2019 DOI: 10.3390/molecules24132417
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