WL
Won Dong Lee
Yonsei University, Princeton University, Technion – Israel Institute of Technology, Seoul National University
Research areas: Biochemistry, Genetics and Molecular Biology · Molecular Biology · Cancer, Hypoxia, and Metabolism · Metabolism, Diabetes, and Cancer · Cancer, Lipids, and Metabolism
0000-0002-2344-171X
Employment
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Yonsei University Assistant Professor2025 - Present
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Princeton University Postdoctoral research associate2019 - 2025
Education
- 2015 - 2019
- 2013 - 2015
- 2006 - 2013
Projects & Funding
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Impact of insulin on lactate metabolism National Institute of Diabetes and Digestive and Kidney Diseases2021 - 2024
Publications (31)
- Mitochondria with (distinct) personality. Save
- A tumor-on-a-chip for in vitro study of CAR-T cell immunotherapy in solid tumors Save
- Acute AKT signaling increases glucose phosphorylation and contribution to glycogen in hepatocytes Save
- Competitive catabolism drives hyperglycemia and hyperinsulinemia in obesity Save
- Emulating the gingival-tooth interface during bacterial, fungal, and viral infection in a microphysiological model of the human oral cavity Save
- Language model-guided anticipation and discovery of mammalian metabolites Save
- Nutrient Availability Dictates Cancer Metabolism–Based Therapeutic Responses to Nononcology Drugs Save
- Precancer exercise capacity and metabolism during tumor development coordinate the skeletal muscle–tumor metabolic competition Save
- Spatial metabolic gradients in the liver and small intestine Save
- Hepatocyte mitochondrial NAD+ content is limiting for liver regeneration Save
- Lactate homeostasis is maintained through regulation of glycolysis and lipolysis Save
- Microbiome metabolism of dietary phytochemicals controls the anticancer activity of PI3K inhibitors Save
- Cardiac NAD+ depletion in mice promotes hypertrophic cardiomyopathy and arrhythmias prior to impaired bioenergetics Save
- A bioengineered model of human placental exposure to environmental metals during pregnancy Save
- NAD+ precursors prolong survival and improve cardiac phenotypes in a mouse model of Friedreich’s Ataxia Save
- Quantification of nutrient fluxes during acute exercise in mice Save
- Selected Ion Monitoring for Orbitrap-Based Metabolomics Save
- mTORC1 controls murine postprandial hepatic glycogen synthesis via Ppp1r3b Save
- Dichloroacetate as a novel pharmaceutical treatment for cancer-related fatigue in melanoma Save
- Impact of acute stress on murine metabolomics and metabolic flux Save