Vandana Mishra

Employment

• USUHS Postdoctoral fellow
  2026 - Present
• National Institutes of Health Postdoc
  2023 - 2025
• National Institutes of Health Postdoc
  2022 - 2023
• Indian Institute of Technology Bombay Research Associate
  2020 - 2022

Education

• University of Mysore Masters
  2010 - 2012

Projects & Funding

Projects & funding information is unavailable.

Publications (8)

• Dimerization-dependent serine protease activity of FAM111A prevents replication fork stalling at topoisomerase 1 cleavage complexes
  Nature Communications 2024 DOI: 10.1038/s41467-024-46207-w
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• Inter-subunit crosstalk via PDZ synergistically governs allosteric activation of proapoptotic HtrA2
  Structure 2022 DOI: 10.1016/j.str.2022.06.001
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• Structures of plasmepsin X from Plasmodium falciparum reveal a novel inactivation mechanism of the zymogen and molecular basis for binding of inhibitors in mature enzyme
  Protein Science 2022 DOI: 10.1002/pro.4279
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• Molecular insights into the inhibition of plasmepsins by HIV-1 protease inhibitors: Implications for antimalarial drug discovery
  2021 DOI: 10.1101/2021.09.27.461917
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• Advancements in macromolecular crystallography: from past to present
  Emerging Topics in Life Sciences 2021 DOI: 10.1042/etls20200316
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• Activation mechanism of plasmepsins, pepsin‐like aspartic proteases from Plasmodium, follows a unique trans‐activation pathway
  The FEBS Journal 2021 DOI: 10.1111/febs.15363
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• Deciphering the mechanism of potent peptidomimetic inhibitors targeting plasmepsins – biochemical and structural insights
  The FEBS Journal 2018 DOI: 10.1111/febs.14598
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• Understanding the structural basis of substrate recognition by Plasmodium falciparum plasmepsin V to aid in the design of potent inhibitors
  Scientific Reports 2016 DOI: 10.1038/srep31420
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