Mara Suleiman

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Publications (50)

• Epigenetic landscapes in human pancreatic islets reveal distinct drivers for adaptation to age and type 2 diabetes
  Nature Communications 2026 DOI: 10.1038/s41467-026-73222-w
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• Metabolomic profile differs between LADA and type 1 diabetes identifying tryptophan metabolism as a pathway involved in the heterogeneity of autoimmune diabetes
  Diabetologia 2026 DOI: 10.1007/s00125-026-06777-4
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• Functional recovery of islet beta cells in human type 2 diabetes: transcriptome signatures unveil therapeutic approaches
  Science Advances 2025 DOI: 10.1126/sciadv.ads2905
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• CD4+ T Cells From Individuals With Type 1 Diabetes Respond to a Novel Class of Deamidated Peptides Formed in Pancreatic Islets
  Aïsha Callebaut, Perrin Guyer, Rita Derua

  +12 more

  • Mijke Buitinga
  • Anthony Manganaro
  • Xiaoyan Yi
  • Fernanda Marques Câmara Sodré
  • Saurabh Vig
  • +7 more
  Diabetes 2024 DOI: 10.2337/db23-0588
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• Differential CpG methylation at Nnat in the early establishment of beta cell heterogeneity
  Diabetologia 2024 DOI: 10.1007/s00125-024-06123-6
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• PNLIPRP1 Hypermethylation in Exocrine Pancreas Links Type 2 Diabetes and Cholesterol Metabolism
  Diabetes 2024 DOI: 10.2337/db24-0215
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• The mitochondrial tRNA-derived fragment, mt-tRF-LeuTAA, couples mitochondrial metabolism to insulin secretion
  Molecular Metabolism 2024 DOI: 10.1016/j.molmet.2024.101955
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• Differential CpG methylation at Nnat in the early establishment of beta cell heterogeneity
  Biorxiv 2023 DOI: 10.1101/2023.02.04.527050
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• A single-cell human islet interactome atlas identifies disrupted autocrine and paracrine communications in type 2 diabetes
  Nar Genomics and Bioinformatics 2022 DOI: 10.1093/nargab/lqac084
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• Epigenetics of PNLIPRP1 in human pancreas reveals a molecular path between type 2 diabetes and pancreatic cancer
  Medrxiv 2022 DOI: 10.1101/2022.12.30.22284058
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• Genetic regulation of RNA splicing in human pancreatic islets
  Genome Biology 2022 DOI: 10.1186/s13059-022-02757-0
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• In depth functional characterization of human induced pluripotent stem cell-derived beta cells in vitro and in vivo
  Frontiers in Cell and Developmental Biology 2022 DOI: 10.3389/fcell.2022.967765
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• Regenerative medicine technologies applied to transplant medicine. An update
  Frontiers in Bioengineering and Biotechnology 2022 DOI: 10.3389/fbioe.2022.1015628
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• The Protective Action of Metformin against Pro-Inflammatory Cytokine-Induced Human Islet Cell Damage and the Mechanisms Involved
  Cells 2022 DOI: 10.3390/cells11152465
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• The Role of Beta Cell Recovery in Type 2 Diabetes Remission
  International Journal of Molecular Sciences 2022 DOI: 10.3390/ijms23137435
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• Arginase 2 and polyamines in human pancreatic beta cells: Possible role in the pathogenesis of type 2 diabetes
  International Journal of Molecular Sciences 2021 DOI: 10.3390/ijms222212099
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• Correction: Integration of single-cell datasets reveals novel transcriptomic signatures of β-cells in human type 2 diabetes (NAR Genomics and Bioinformatics (2020) 2 (lqaa097) DOI: 10.1093/nargab/lqaa097)
  Nar Genomics and Bioinformatics 2021 DOI: 10.1093/nargab/lqab053
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• Genetic regulation of RNA splicing in human pancreatic islets
  Biorxiv 2021 DOI: 10.1101/2021.11.11.468254
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• Mast cells and the pancreas in human type 1 and type 2 diabetes
  Cells 2021 DOI: 10.3390/cells10081875
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• Noradrenergic fibers are associated with beta-cell dedifferentiation and impaired beta-cell function in humans
  Metabolism Clinical and Experimental 2021 DOI: 10.1016/j.metabol.2020.154414
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