Jan Paulo Zaragoza

Employment

• University of California Berkeley Postdoctoral Fellow
  2018 - Present

Education

• Johns Hopkins University PhD in Chemistry
  2012 - 2017

Projects & Funding

Projects & funding information is unavailable.

Publications (14)

• Structural Characterization of Linker Shielding in ADC Site-Specific Conjugates
  Pharmaceutics 2025 DOI: 10.3390/pharmaceutics17121568
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• Temporal and spatial resolution of distal protein motions that activate hydrogen tunneling in soybean lipoxygenase
  Proceedings of the National Academy of Sciences 2023 DOI: 10.1073/pnas.2211630120
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• Temporal and Spatial Resolution of a Protein Quake that Activates Hydrogen Tunneling in Soybean Lipoxygenase
  2022 DOI: 10.1101/2022.03.31.486235
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• Biochemical and crystallographic investigations into isonitrile formation by a nonheme iron-dependent oxidase/decarboxylase
  Journal of Biological Chemistry 2021 DOI: 10.1074/jbc.RA120.015932
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• Hydroxyl Transfer to Carbon Radicals by Mn(OH) vs Fe(OH) Corrole Complexes
  Daniel C. Cummins, Jessica G. Alvarado, Jan Paulo T. Zaragoza +4 more
  Inorganic Chemistry 2020 DOI: 10.1021/acs.inorgchem.0c02640
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• Hydrogen Atom Abstraction by High-Valent Fe(OH) versus Mn(OH) Porphyrinoid Complexes: Mechanistic Insights from Experimental and Computational Studies
  Jan Paulo T. Zaragoza, Daniel C. Cummins, M. Qadri E. Mubarak +3 more
  Inorganic Chemistry 2019 DOI: 10.1021/acs.inorgchem.9b02923
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• Detecting and Characterizing the Kinetic Activation of Thermal Networks in Proteins: Thermal Transfer from a Distal, Solvent-Exposed Loop to the Active Site in Soybean Lipoxygenase
  The Journal of Physical Chemistry B 2019 DOI: 10.1021/acs.jpcb.9b07228
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• A Reactive Manganese(IV)–Hydroxide Complex: A Missing Intermediate in Hydrogen Atom Transfer by High-Valent Metal-Oxo Porphyrinoid Compounds
  Journal of the American Chemical Society 2018 DOI: 10.1021/jacs.8b00350
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• Biomimetic Reactivity of Oxygen-Derived Manganese and Iron Porphyrinoid Complexes
  Chemical Reviews 2017 DOI: 10.1021/acs.chemrev.7b00180
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• Direct Observation of Oxygen Rebound with an Iron-Hydroxide Complex
  Journal of the American Chemical Society 2017 DOI: 10.1021/jacs.7b07979
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• meso-N-Methylation of a porphyrinoid complex: activating the H-atom transfer capability of an inert ReV(O) corrolazine
  Chemical Communications 2017 DOI: 10.1039/C6CC09341H
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• The Influence of Peripheral Substituent Modification on PV, MnIII, and MnV(O) Corrolazines: X-ray Crystallography, Electrochemical and Spectroscopic Properties, and HAT and OAT Reactivities
  Inorganic Chemistry 2016 DOI: 10.1021/acs.inorgchem.6b01219
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• Rhenium(v)–oxo corrolazines: isolating redox-active ligand reactivity
  Chem. Commun. 2016 DOI: 10.1039/c5cc07956j
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• Strong Inhibition of O-Atom Transfer Reactivity for MnIV(O)(π-Radical-Cation)(Lewis Acid) versus MnV(O) Porphyrinoid Complexes
  Journal of the American Chemical Society 2015 DOI: 10.1021/jacs.5b00875
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