Sharmila Shekhar Mande
Tata Consultancy Services Ltd, Tata Consultancy Services (India), Indian Institute of Science
0000-0002-2614-1982
About
I am a computational biologist who joined Tata Consultancy Services (TCS) in 2001 to establish a Bioinformatics R&D group. Over the years, I have built, trained, and mentored a highly interdisciplinary team within an IT industry setting, creating a world-class research group committed to excellence in both fundamental and translational research. Our work has focused on developing innovative algorithms for the analysis, visualization, and modeling of complex omics data, including genomics and metagenomics.
During more than two decades at TCS Research, I spearheaded several Public–Private Partnership projects involving leading National and International academic institutions, research organizations, and hospitals. I was among the early pioneers in India to initiate cutting-edge research in the niche fields of ‘Microbiome and Metagenomics’. My group has developed a range of algorithms and solutions with strong translational potential, including microbiome-based biomarkers for disease diagnosis, health monitoring, and novel strategies for applications such as bioremediation. The impact of this work is reflected in over 100 granted patents, in addition to numerous publications in peer-reviewed international journals.
Following my superannuation in August 2022, I continued to serve as an Advisor to Life Sciences Research at TCS until March 2026. I currently hold the AYUSH Distinguished Scientist Chair awarded by the Ministry of AYUSH, Government of India. In this role, I mentor AYUSH clinicians and students in understanding Indian traditional knowledge systems through modern scientific approaches.
In addition, I serve as a Visiting Professor at the Indian Institute of Technology (IIT) Kanpur, IIT Gandhinagar, and the Indian Institute of Science Education and Research (IISER) Thiruvananthapuram. I am also an Adjunct Professor at the Indraprastha Institute of Information Technology (IIIT) Delhi and Indian Institute of Information Technology, Surat.
I have served and continue to serve on advisory bodies of several government agencies and premier academic institutions, including IITs, National Institute of Technology (NITs), IISERs, IIITs, Universities, and other research organizations. I have also contributed as an expert committee member for agencies such as Indian National Academy of Engineering (INAE), Department of Science and Technology (DST), and Indian Council of Medical Research (ICMR), as well as for mission-mode projects supported by the Office of the Principal Scientific Advisor (PSA) to the Government of India. Currently, I serve on the Academic and Scientific Advisory Boards of IISER Berhampur, the Institute of Bioinformatics and Applied Biotechnology (IBAB), and the All India Institute of Ayurveda (AIIA).
I am an elected Fellow of the Indian National Academy of Engineering (INAE) and the Indian National Science Academy (INSA). I am a recipient of the TATA Innovista Award for developing innovative methodologies to predict the risk of diseases and disorders. I have also been featured in the compendium of “75 Women Engineers in India,” published by INAE under the aegis of the ‘Azadi Ka Amrit Mahotsav’ celebrations. In addition, I have served as an Editorial Board Member of the international peer-reviewed journal Gut Pathogens.
Employment
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Tata Consultancy Services Ltd Distinguished Chief Scientist2020 - 2022
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Tata Consultancy Services (India) Chief Scientist2017 - 2019
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Tata Consultancy Services (India) Head, Bio-Sciences Research2012 - 2017
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Tata Consultancy Services (India) Head, Bioinformatics Division2001 - 2011
Education
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Indian Institute of Science PhD1985 - 1991
Projects & Funding
Projects & funding information is unavailable.
Publications (204)
- Should probiotic recommendation be customized to diet and gut microbiota make-up? Insights from in silico metabolic simulations Save
- Method and system for evaluating and reducing the degree of mosquito attractiveness of individual Save
- Designing a personalized composition for counteracting skin malodor Save
- Method and system for simultaneous interpretation of taxonomic distribution and replication rates of microbial communities Save
- Method and system for annotation and classification of biomedical text having bacterial associations Save
- Method and system for monitoring the gut health of an individual Save
- Method and system for designing personalized therapeutics and diet based on functions of microbiome Save
- Method and system for risk assessment of autism spectrum disorder in a subject Save
- Method and system for preparing knowledgebase of microbes and microbial functions helping to reduce cancer risk Save
- System and method for bioremediation of pollutants Save