Wayde Veldman
Inqaba Biotec, Lancet Laboratories, Rhodes University, Tshwane University of Technology
0000-0002-2747-7146
About
I am a South African structural bioinformatician with four years of postdoctoral experience, specialising in enzyme MD simulations — particularly using residue interaction networks to predict the allosteric effects caused by residue variations and/or binding of ligands.
Areas of skill:
• Protein structure, dynamics, and interactions
• Molecular dynamics simulations and analysis
• Molecular sequence analyses
• Homology modeling
• In silico docking
• Python, R, MATLAB, Linux, Bash, Pymol, VMD, Modeller, DiscoveryStudio, Schrödinger, RCSB PDB, Jupyter, Git, Chimera, GROMACS, Autodock, binding free energy, GWAS, NMA, PCA, FEL, FEP
• High-performance computing
• Scientific/academic writing
• Data analysis
• In silico high-throughput screening for drug discovery
• PCR, gel electrophoresis, DNA sequencing, human and plant pathology, lab work, HPLC
Achievements:
• I have developed Python scripts for MD analysis that have been universally adopted by my current group.
• I have been involved in nine publications in reputable international science journals (five as first author) with over 300 citations.
• I have been awarded the South African NRF scarce skills postdoctoral fellowship and Rhodes University postdoctoral fellowship.
I have a special affinity for science which instills curiosity and enthusiasm for all knowledge. I have incorporated many scientific concepts and ideas into consciousness through dozens of popular science books - ranging from genetics and nuclear physics to astronomy and philosophy - written by the world's most accomplished scientists and thinkers.
I like football, golf, and various other sports. I have been playing guitar for 21 years, the drums for 2, and have had the pleasure of playing in numerous bands, meeting all kinds of people along the way.
Employment
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Inqaba Biotec Lab Technician2014 - 2014
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Lancet Laboratories Student Medical Technician2011 - 2016
Education
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Rhodes University Ph.D.2018 - Present
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Tshwane University of Technology Magister Technologiae2014 - 2016
Projects & Funding
Projects & funding information is unavailable.
Publications (10)
- Decoding Allosteric Effects of Missense Variations in Drug Metabolism: Afrocentric CYP3A4 Alleles Explored Save
- Residue Variations in Human N-Acetyltransferase 2 Enzyme Alleles: From Rapid to Slow Acetylation Save
- Allosteric modulation of Plasmodium falciparum Isoleucyl tRNA synthetase by South African natural compounds Save
- Human Cytochrome P450 1, 2, 3 Families as Pharmacogenes with Emphases on Their Antimalarial and Antituberculosis Drugs and Prevalent African Alleles Save
- Sequence, structure, dynamics, and substrate specificity analyses of bacterial Glycoside Hydrolase 1 enzymes from several activities Save
- Differences in Gluco and Galacto Substrate-Binding Interactions in a Dual 6Pβ-Glucosidase/6Pβ-Galactosidase Glycoside Hydrolase 1 Enzyme from Bacillus licheniformis Save
- X‑ray Structure, Bioinformatics Analysis, and Substrate Specificity of a 6‑Phospho-β-glucosidase Glycoside Hydrolase 1 Enzyme from Bacillus licheniformis Save
- Integrated Computational Approaches and Tools for Allosteric Drug Discovery Save
- Biocontrol of Fusarium mangiferae responsible for mango malformation using bacterial isolates Save
- Application of essential oils as multi-target fungicides for the control of Geotrichum citri-aurantii and other postharvest pathogens of citrus Save