Ahmed Moustafa Mohamed Elsayed
Also known as: Ahmed Mostafa, Ahmed M. Elsayed
Justus-Liebig University Giessen - Faculty of Medicine, Zagazig University Faculty of Pharmacy
Research areas: Medicine · Epidemiology · Influenza Virus Research Studies · SARS-CoV-2 and COVID-19 Research · Virology and Viral Diseases
0000-0002-2878-5714
About
My research focuses on the evolution, pathogenesis, and zoonotic transmission of emerging and reemerging viruses, with particular emphasis on influenza viruses. I investigate the molecular determinants of viral replication, host adaptation, pathogenicity, and cross-species transmission and translate these findings into the development of recombinant vaccines and antiviral strategies. My current work at Texas Biomedical Research Institute focuses on emerging H5N1 viruses, including cattle-origin strains, using reverse genetics, viral genome sequencing, reporter-virus systems, and preclinical models.
I have extensive experience working in high-containment environments, including BSL-2/3 and BSL-4, and am currently in Phase 4 of ABSL-4 training. My long-term goal is to integrate molecular virology, viral evolution, and translational research to identify determinants of zoonotic emergence and develop broadly protective vaccines and antiviral interventions, strengthening preparedness against future emerging viral threats.
Employment
Employment history is unavailable.
Education
-
Justus-Liebig University Giessen - Faculty of Medicine Doctoral degree (Dr. biol. hom)2012 - 2015
-
Zagazig University Faculty of Pharmacy Master of Pharmaceutical sciences (Research, Microbiology)2006 - 2009
-
Zagazig University Faculty of Pharmacy Bachelor of Pharmaceutical sciences2000 - 2005
Projects & Funding
Projects & funding information is unavailable.
Publications (186)
- Mice immunized with N1 neuraminidase in a single cycle infectious virus or in a recombinant nanoparticle vaccine are protected against lethal challenge with highly pathogenic avian influenza H5N1 influenza Save
- NS-segment-based reporter influenza A viruses: engineering strategy, applications, and limitations Save
- Enhanced Pathogenicity and Contact Transmissibility of Human-origin Avian Influenza H5N1 Clade 2.3.4.4b Genotype B3.13 Compared to D1.1 in Ferrets Save
- Host-specific functional evolution of seal influenza A virus NS1 protein following avian-to-seal transmission Save
- Newcastle disease virus: global distribution, molecular insights and implications for biotechnology and translational Research Save
- The Emerging Threat of Monkeypox: An Updated Overview Save
- Genetic characterization of highly pathogenic avian influenza A/H5N8 virus isolated from commercial poultry farms in Egypt reveals zoonotic potential Save
- A bireporter recombinant SARS-CoV-2 Omicron BA.5 for in vitro and in vivo studies Save
- A single PA-X mutation in bovine-origin H5N1 influenza virus reduces pathogenicity in mice Save
- Anti-COVID-19 activity and simple HPLC method for concurrent detection of repurposed drugs in novel binary mixtures Save
- Comprehensive evaluation of Balanites aegyptiaca extracts: in vitro bioactivities and in vivo antimicrobial efficacy and hematological impact on broiler chickens challenged with E. coli O78 and Clostridium perfringens type A Save
- Correction: Scrutinizing the Feasibility of Nonionic Surfactants to Form Isotropic Bicelles of Curcumin: a Potential Antiviral Candidate Against COVID-19 (AAPS PharmSciTech, (2021), 23, 1, (44), 10.1208/s12249-021-02197-2) Save
- Neuraminidase-Based Cross-Protective Immunity against H5N1 Influenza Viruses in Humans Save
- Pre-existing and cross-reactive immunity to avian influenza H5N1 in humans: Implications for pandemic risk and vaccine strategies Save
- Pulmonary Microvascular Endothelial Antigen Presentation Activates Resident CD8+ T Cells to Restrain Influenza Lung Injury Save
- Replication kinetics, pathogenicity and virus-induced cellular responses of cattle-origin influenza A(H5N1) isolates from Texas, United States Save
- Bioluminescent reporter influenza A viruses to track viral infections Save
- A live attenuated NS1-deficient vaccine candidate for cattle-origin influenza A (H5N1) clade 2.3.4.4.b viruses Save
- A Live Attenuated Vaccine Candidate against Emerging Highly Pathogenic Cattle-Origin 2.3.4.4b H5N1 Viruses Save
- A Human H5N1 Influenza Virus Expressing Bioluminescence for Evaluating Viral Infection and Identifying Therapeutic Interventions Save