KK
Kevser Kübra Kırboğa
Bilecik Şeyh Edebali Üniversitesi Mühendislik Fakültesi
Research areas: Pharmacology, Toxicology and Pharmaceutics · Drug Discovery · Computational Drug Discovery Methods · Protein Structure and Dynamics · Cholinesterase and Neurodegenerative Diseases
0000-0002-2917-8860
Employment
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Bilecik Şeyh Edebali Üniversitesi Mühendislik Fakültesi Research Assistant2022 - Present
Education
Education history is unavailable.
Projects & Funding
Projects & funding information is unavailable.
Publications (48)
- Deep mutational scanning of CYP2C9, CYP2C19, and NUDT15 shows that pharmacogene variant interpretation requires assay-specific functional data Save
- Decoding PI3K isoform selectivity through an ensemble-based framework integrating correlated motions, allosteric networks, and hydration thermodynamics Save
- Quinoline and Phthalimide Substituted Silicon Phthalocyanines as Multi‐Target Inhibitors of Cholinesterases and Carbonic Anhydrases Save
- Steric Control of Competitive Versus Noncompetitive Lactoperoxidase Inhibition by Amide‐Linked Iridium(III) Complexes Save
- Directional information flow in human frataxin defines allosteric pathways connecting the hydrophobic core to the iron‐binding ridge Save
- Evaluation of Ion Channel Blockers as Cholinesterase Inhibitors for Alzheimer's Disease: An Integrated In Vitro, In Silico, and DFT Study Save
- Sulfonamide Derivatives as Competitive Lactoperoxidase Inhibitors Through Integrated Experimental and Multi‐Level Computational Analysis Save
- Signal Processing and Dimensionality Reduction Algorithms for High-Dimensional Time-Series Data Applied to Biomolecular Simulations Save
- Thermodynamic Preference of Fe2+ for a C-Terminal Coordination Site in Human Frataxin Revealed by Multiscale Simulations Save
- Integration of Evolutionary Analysis With RFdiffusion for De Novo Design of Aggregation‐Resistant Frataxin Save
- Potent Multi‐Target Inhibition of Cholinesterases and Carbonic Anhydrases by Iridium(III)–Phenanthroline Derivatives: Integrated Structure–Activity Relationship, Molecular Docking and Anticancer Cell Culture Studies Save
- Energy-driven innovations in computational de novo protein engineering Save
- Structure-Based Virtual Screening of Plant-Derived Flavonoids as Putative GLUT9 Binders with Antioxidant Properties Save
- Neuroprotective potential of Garcinia extracts against diabetic peripheral neuropathy: GC–MS profiling, network pharmacology, molecular docking, and in vitro studies Save
- Identification of potential antigenic proteins and epitopes for the development of a monkeypox virus vaccine: an in silico approach Save
- Explainable machine learning for statistical prediction of polymer fiber properties using process parameters Save
- Tumor Microenvironment in Ovarian Cancer through Spatial Transcriptomics and Identification of Key Gene Expression Profiles Save
- Bioinformatics-Driven Structural and Pharmacological Analysis of SLITRK1 in Tourette Syndrome: Impact of S656M Mutation Using Molecular Dynamics, Docking, and Reinforcement Learning Save
- Exploring the Genome-wide Expression Level of the Bacterial Strain Belonging to Bacillus safensis (MM19) Against Phomopsis viticola Save
- Spectrochemical and explainable artificial intelligence approaches for molecular level identification of the status of critically ill patients with COVID-19 Save