Stavros Loukogeorgakis
University College London, Great Ormond Street Hospital, Queen Mary University of London, University College London Hospitals NHS Foundation Trust
Research areas: Medicine · Cardiology and Cardiovascular Medicine · Mesenchymal stem cell research · Cardiac Ischemia and Reperfusion · Tissue Engineering and Regenerative Medicine
0000-0002-2960-5252
About
I am the Associate Professor of Paediatric Surgery at the UCL Great Ormond Street Institute of Child Health and a Consultant Neonatal and Paediatric Surgeon at Great Ormond Street Hospital (GOSH) and University College London Hospitals (UCLH). I am a member of the colorectal service at the department of Specialist Neonatal and Paediatric Surgery, GOSH, as well as a member of the fetal surgery team at the Centre for Prenatal Therapy, UCLH. I have an academic interest in prenatal treatment of congenital diseases, as well as the development of novel, minimally invasive treatment platforms for fetal and neonatal therapy. I have a total of 79 peer reviewed publications and have obtained a total of over £3.5 million in research grants as primary applicant or co-applicant. I lead a research group working on fetal immunological responses to fetal intervention, and identifying novel stem cell sources for in utero transplantation and other pre/postnatal regenerative medicine applications. Moreover, my group are investigating the utility of nanotechnology and artificial intelligence/machine learning for pre/postnatal diagnosis and treatment of rare congenital and acquired diseases.
Employment
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University College London Associate Professor in Paediatric Surgery2021 - Present
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Great Ormond Street Hospital Consultant Neonatal and Paediatric Surgeon2021 - Present
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University College London Hospitals NHS Foundation Trust Consultant Neonatal and Paediatric Surgeon2021 - Present
Education
- 2003 - 2005
- 2000 - 2007
- 1997 - 2000
Projects & Funding
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In Utero Non-Viral Gene Editing for Krabbe Disease Medical Research Council2024 - 2027
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Prenatal Repair of Spina Bifida: Towards a Minimally Invasive (Fetoscopic) Approach NIHR Great Ormond Street Hospital Biomedical Research Centre2024 - 2027
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In Utero Cell Therapy for Alpha Thalassaemia LifeArc2023 - 2026
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Development of a Clinically and Regulatory Approvable Exosome-Based Treatment for Necrotizing Enterocolitis Medical Research Council2023 - 2027
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Derivation of patient specific fetal fluid-derived lung organoids to develop and test prenatal treatments for Congenital Diaphragmatic Hernia NIHR Great Ormond Street Hospital Biomedical Research Centre2023 - 2024
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Haematopoietic Potential of Amniotic Fluid Stem Cells for Prenatal Therapy UCL2023 - 2024
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Development of Synthetic Nanoparticles for Non-Viral Gene Therapy In Vivo NIHR Great Ormond Street Hospital Biomedical Research Centre2022 - 2023
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Single Cell RNA Sequencing of Amniotic Fluid Stem Cells NIHR Great Ormond Street Hospital Biomedical Research Centre2022 - 2023
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Haemoglobinopathies as Target for Fetal Transplantation Medical Research Council2020 - 2023
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Prenatal Stem Cell-Gene Therapy for Wilson’s Disease Using Amniotic Fluid Stem Cells Wellcome Trust2012 - 2015
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Exercise-induced protection against ischaemia-reperfusion injury British Heart Foundation2010 - 2012
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Renal Protection against Ischaemia-Reperfusion in Transplantation – REPAIR Trial National Institute for Health Research2009 - 2014
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Mechanisms of post-conditioning in humans British Heart Foundation2006 - 2009
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Characterisation of Remote Ischaemic Preconditioning in Humans British Heart Foundation2003 - 2005
Publications (81)
- FACTORS ASSOCIATED WITH SHORT- AND LONG-TERM SURVIVAL IN OESOPHAGEAL ATRESIA WITH TRACHEOESOPHAGEAL FISTULA Save
- The Management of Internal Fistulizing Crohn’s Disease in a Child: More Than Meets the Eye Save
- Prenatal VEGF Nano-Delivery Reverses Congenital Diaphragmatic Hernia-associated Pulmonary Abnormalities Save
- Author Correction: Single-cell guided prenatal derivation of primary fetal epithelial organoids from human amniotic and tracheal fluids Save
- Diagnosing Necrotizing Enterocolitis via Fine-Grained Visual Classification Save
- STAT trial: stoma or intestinal anastomosis for necrotizing enterocolitis: a multicentre randomized controlled trial Save
- Bowel Function Score in Long-Term Follow-Up for Children with Hirschsprung Disease: OASIS-Holistic Care in Hirschsprung Disease Network Position Paper Save
- Influence of Diet on Bowel Function and Abdominal Symptoms in Children and Adolescents with Hirschsprung Disease—A Multinational Patient-Reported Outcome Survey Save
- Letter to the Editor re: re: ultrasound as the first line investigation for midgut malrotation: a UK tertiary centre experience Save
- Validation of the Clavien-Madadi Classification for Unexpected Events in Pediatric Surgery: A Collaborative ERNICA Project Save
- An investigation into augmentation and preprocessing for optimising X-ray classification in limited datasets: a case study on necrotising enterocolitis Save
- Transitional Care In Patients With Hirschsprung Disease: Those Left Behind Save
- Single-cell guided prenatal derivation of primary fetal epithelial organoids from human amniotic and tracheal fluids Save
- Short and Medium Term Outcomes of Open and Laparoscopic Assisted Oesophageal Replacement Procedures Save
- Thoracoscopic Stage Internal Traction Repair Reduces Time to Achieve Esophageal Continuity in Long Gap Esophageal Atresia Save
- Ultrasound as the first line investigation for midgut malrotation: a UK tertiary centre experience. Save
- Outcomes 1 year after non-operative management of uncomplicated appendicitis in children: Children with AppendicitiS during the CoronAvirus panDEmic (CASCADE) study. Save
- Thoracoscopic vs open repair of congenital diaphragmatic hernia after extracorporeal membrane oxygenation: a comparison of intra-operative data. Save
- Fetal allotransplant recipients are resistant to graft-versus-host disease. Save
- Congenital diaphragmatic hernia subtypes: Comparing birth prevalence, occurrence by maternal age, and mortality in a national birth cohort. Save