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Saugata Hazra

Indian Institute of Technology Roorkee, Albert Einstein College of Medicine, University of Illinois at Chicago, Indian Institute of Technology Kharagpur, Saint Jude Children's Research Hospital

ORCID iD 0000-0002-3074-1534
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About

Saugata Hazra, PhD, is a Professor at the Indian Institute of Technology Roorkee (Department of Biosciences & Bioengineering). Trained as a biochemist and biophysicist with a specialization in structure-based drug design, Dr. Hazra leads an interdisciplinary research program addressing mechanisms of antimicrobial resistance (AMR). His laboratory studies enzymes that underpin resistance and essential bacterial pathways, including peptidoglycan synthesis and folate biosynthesis, using an integrated toolkit of protein crystallography, enzymology, biophysical assays, computational biology, molecular dynamics, virtual screening, and macromolecular interaction analyses. The Hazra Lab combines structural, biochemical and computational approaches to dissect catalytic divergence, elucidate structure–function relationships, and guide the discovery of inhibitors and diagnostics with novel mechanisms of action. Current projects emphasize the characterization of pathologically important bacterial proteins to inform rational antibiotic design and translational strategies to counteract drug resistance. Dr. Hazra is committed to bridging fundamental enzymology with practical therapeutics development and to training the next generation of scientists in interdisciplinary methods for tackling AMR.

Research interests: Antibacterial Resistance

NGS Data, Genome, Metagenome

Structural Biology & Protein Crystallography

Structure-based Drug Discovery & Virtual Screening

Enzymology & Enzyme Kinetics

Biophysical and Biochemical Characterization

Structure–Function Relationship Analysis

Computational Biology & Molecular Dynamics (MD) Simulations

Macromolecular Interactions and Mechanistic Studies

Development of Diagnostics and Therapeutics for AMR

https://www.saugatahazralab.com/

Employment

  • Indian Institute of Technology Roorkee Professor
    2025 - Present
  • Indian Institute of Technology Roorkee Associate Professor
    2021 - 2024
  • Indian Institute of Technology Roorkee Assistant Professor
    2014 - 2021
  • Albert Einstein College of Medicine Postdoctoral Scientist
    2011 - 2014
  • Saint Jude Children's Research Hospital Postdoctoral Researcher
    2010 - 2011

Education

  • University of Illinois at Chicago PhD
    2004 - 2010
  • Indian Institute of Technology Kharagpur MTech
    2002 - 2004
  • University of Calcutta MSc
    2000 - 2002
  • University of Calcutta BSc
    1997 - 2000

Projects & Funding

Projects & funding information is unavailable.

Publications (96)