Debanjana Das
The University of Texas Southwestern Medical Center, Tata Institute of Fundamental Research
0000-0002-3178-7526
About
My research background is in protein biophysics. My academic journey has involved the study of metalloproteins, specifically azurin. During my doctoral research, I delved into the intriguing topic of circular permutation and its impact on the energy landscape of azurin. Circular permutation alters the sequence of amino acids in a protein without changing its native structure.
Prior to that, in my Master’s thesis, I focused on understanding the metal-binding characteristics of small peptides derived from azurin. This work was crucial in shedding light on how these peptides interact with metal ions.
In essence, my work has revolved around gaining a deeper understanding of the structure-function relationship in metalloproteins, using azurin as a model system. This knowledge is fundamental to the development of bio-inspired materials and therapeutics.
Employment
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The University of Texas Southwestern Medical Center Post-doctoral researcher2024 - Present
Education
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Tata Institute of Fundamental Research Ph.D.2020 - 2024
Projects & Funding
Projects & funding information is unavailable.
Publications (8)
- Protein Stability Regulated by Tag- and Site-Specific Ubiquitination and SUMOylation Save
- Electrostatics Govern Protein Orientation on Citrate-Capped Gold Nanoparticles Save
- Circular permutants of azurin exhibit molten globule intermediates not observed in WT azurin Save
- Protein engineering using circular permutation – structure, function, stability, and applications Save
- Circular permutation at azurin’s active site slows down its folding Save
- Metal‐binding and circular permutation‐dependent thermodynamic and kinetic stability of azurin Save
- Azurin-Derived Peptides: Comparison of Nickel- And Copper-Binding Properties Save
- Copper-induced spectroscopic and structural changes in short peptides derived from azurin Save