Paola Niola

About

I hold a Bachelor's degree in Experimental Biology and a Master's degree in Neurobiology from the University of Cagliari (Italy). In 2016, I completed a PhD in Neuroscience, focusing on the genetic role of microRNAs as peripheral biomarker in bipolar suicide patients. During my PhD, I had the opportunity to spend three months at the Advance Sequencing Facility at the Francis Crick Institute (London, UK) where I gained expertise in next generation sequencing. I joined UCL Genomics in April 2016 where I am a lead applications specialist in QC platforms and sequencing, mainly dealing with sample quality control and sequencing projects (library preparation and sequencing) using Illumina platforms.

Employment

• Immunocore (United Kingdom) Research Scientist
  2023 - Present
• University College London NGS Applications Specialist
  2016 - 2023

Education

Education history is unavailable.

Projects & Funding

Projects & funding information is unavailable.

Publications (11)

• Sex differences in early human fetal brain development
  2024 DOI: 10.1101/2024.03.04.583285
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• Pathogenic variants in the human m6A reader YTHDC2 are associated with primary ovarian insufficiency.
  JCI insight 2022 DOI: 10.1172/jci.insight.154671
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• Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity.
  Cell 2020 DOI: 10.1016/j.cell.2020.11.020
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• MicroRNA expression profiling of lymphoblasts from bipolar disorder patients who died by suicide, pathway analysis and integration with postmortem brain findings.
  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2020 DOI: 10.1016/j.euroneuro.2020.03.005
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• Evidence towards RNA Binding Motif (RNP1, RRM) Protein 3 (RBM3) as a Potential Biomarker of Lithium Response in Bipolar Disorder Patients.
  Journal of molecular neuroscience : MN 2017 DOI: 10.1007/s12031-017-0938-5
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• Co-Variation of Peripheral Levels of miR-1202 and Brain Activity and Connectivity During Antidepressant Treatment.
  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2017 DOI: 10.1038/npp.2017.9
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• Pharmacogenetics of lithium effects on glomerular function in bipolar disorder patients under chronic lithium treatment: a pilot study.
  Neuroscience letters 2016 DOI: 10.1016/j.neulet.2016.12.001
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• Leukocyte telomere length positively correlates with duration of lithium treatment in bipolar disorder patients.
  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2016 DOI: 10.1016/j.euroneuro.2016.03.020
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• Preliminary Transcriptome Analysis in Lymphoblasts from Cluster Headache and Bipolar Disorder Patients Implicates Dysregulation of Circadian and Serotonergic Genes.
  Journal of molecular neuroscience : MN 2015 DOI: 10.1007/s12031-015-0567-9
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• Lithium-induced differential expression of SAT1 in suicide completers and controls is not correlated with polymorphisms in the promoter region of the gene.
  Psychiatry research 2014 DOI: 10.1016/j.psychres.2014.09.014
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