DC
Daniel Coleman
Oregon Health & Science University, Portland Community College, Oregon State University, University of Oregon, Southern Oregon University
Research areas: Biochemistry, Genetics and Molecular Biology · Molecular Biology · Chromatin Remodeling and Cancer · Acute Myeloid Leukemia Research · Protein Degradation and Inhibitors
0000-0002-3414-3160
Employment
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Oregon Health & Science University Alliance Manager2021 - Present
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Oregon Health & Science University Staff Scientist2019 - 2021
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Oregon Health and Science University Assistant Staff Scientist2019 - 2019
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Portland Community College Part-Time Instructor2018 - 2019
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Oregon Health & Science University Postdoctoral Researcher2014 - 2019
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Oregon State University Graduate Research Assistant2009 - 2014
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Marker Gene Technologies Research Assistant2006 - 2008
Education
- 2008 - 2014
- 2003 - 2006
- 2001 - 2003
Projects & Funding
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Training in the Molecular Basis of Skin/Mucosa Pathobiology National Cancer Institute2004 - 2019
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Integrated Regional Training Program in Environmental Health Sciences National Institute of Environmental Health Sciences1979 - 2020
Publications (25)
- BET Bromodomain Inhibition Blocks an AR-Repressed, E2F1-Activated Treatment-Emergent Neuroendocrine Prostate Cancer Lineage Plasticity Program Save
- ASXL1 directs neutrophilic differentiation via modulation of MYC and RNA polymerase II Save
- Alternative splicing of LSD1+8a in neuroendocrine prostate cancer is mediated by SRRM4 Save
- Combined inhibition of JAK/STAT pathway and lysine-specific demethylase 1 as a therapeutic strategy in CSF3R/CEBPA mutant acute myeloid leukemia Save
- Molecular Testing Identifies Determinants of Exceptional Response and Guides Precision Therapy in a Patient with Lethal, Treatment-emergent Neuroendocrine Prostate Cancer Save
- BET bromodomain inhibition blocks the function of a critical AR-independent master regulator network in lethal prostate cancer. Save
- Maintenance of MYC expression promotes de novo resistance to BET bromodomain inhibition in castration-resistant prostate cancer. Save
- PNAS Plus Significance Statements. Save
- LSD1 activates a lethal prostate cancer gene network independently of its demethylase function. Save
- Integrative molecular network analysis identifies emergent enzalutamide resistance mechanisms in prostate cancer. Save
- IL-1 Receptor-Knockout Mice Develop Epidermal Cysts and Show an Altered Innate Immune Response after Exposure to UVB Radiation. Save
- Cellular androgen content influences enzalutamide agonism of F877L mutant androgen receptor. Save
- Coibamide A, a natural lariat depsipeptide, inhibits VEGFA/VEGFR2 expression and suppresses tumor growth in glioblastoma xenografts. Save
- Loss of keratinocytic RXRα combined with activated CDK4 or oncogenic NRAS generates UVB-induced melanomas via loss of p53 and PTEN in the tumor microenvironment. Save
- Retinoid-X-receptors (α/β) in melanocytes modulate innate immune responses and differentially regulate cell survival following UV irradiation. Save
- Grp1-associated scaffold protein regulates skin homeostasis after ultraviolet irradiation. Save
- Endothelin-1 is a transcriptional target of p53 in epidermal keratinocytes and regulates ultraviolet-induced melanocyte homeostasis. Save
- Modified luciola cruciata luciferase gene and protein Save
- RXRα ablation in epidermal keratinocytes enhances UVR-induced DNA damage, apoptosis, and proliferation of keratinocytes and melanocytes. Save
- MODIFIED LUCIOLA CRUCIATA LUCIFERASE PROTEIN Save