ABHISHEK GARG

About

I am a PhD candidate at the University of Delhi, South Campus (expected May 2026), with a focused research program to understand how multilayered bacterial signal transduction networks—spanning two-component histidine kinase (HK) systems and serine/threonine protein kinases (STPKs)—enable Mycobacterium tuberculosis survival and persistence. My doctoral work has established STPK-mediated phosphorylation of histidine kinases as a critical regulatory mechanism and novel therapeutic target for TB drug development. I have deep expertise in kinase biochemistry, phosphoproteomics, protein-protein interaction assays, structural biology, and drug discovery screening.

Employment

• University of Delhi PhD Candidate
  2023 - Present

Education

Education history is unavailable.

Projects & Funding

Projects & funding information is unavailable.

Publications (5)

• Tamoxifen inhibits histidine kinases of M. tuberculosis two-component signaling systems
  Microbiology Spectrum 2026 DOI: 10.1128/spectrum.01880-25
  +Save
• Ser/Thr phosphorylation of Mycobacterium tuberculosis type II RelK toxin by PknK destabilizes TA interaction and interferes with toxin neutralization
  mBio 2025 DOI: 10.1128/mbio.01068-25
  +Save
• In silico evidence for extensive Ser/Thr phosphorylation of Mycobacterium tuberculosis two-component signalling systems
  Current Science 2022 DOI: 10.18520/cs/v123/i9/1164-1169
  +Save
• Identification and characterization of Poly(ADP-ribose) polymerase-1 interacting proteins during development of Dictyostelium discoideum
  Protein Expression and Purification 2021 DOI: 10.1016/j.pep.2021.105923
  +Save
• Insights into the functional aspects of poly(ADP‐ribose) polymerase‐1 (PARP‐1) in mitochondrial homeostasis in Dictyostelium discoideum
  Biology of the Cell 2020 DOI: 10.1111/boc.201900104
  +Save