Vidya Rajasekaran
Also known as: Vidya Rajasekaran-Sutherland
University of Edinburgh, Aston University, Newcastle University, Manipal University
About
My role revolves around investigating mouse models of novel colorectal cancer risk loci, to understand heritable genetic risk loci and how they contribute to CRC predisposition, elucidating functional consequences of such inherited genetic risk factors and impacts of environmental factors on these functions, and how we might mitigate cancer using therapeutics. I am a skilled cell and molecular biologist and am constantly improving and increasing my understanding of mouse physiology and histopathology over the last decade. I have contributed greatly to the development of the Home Office Project licence required for the mouse work and am also responsible for managing all administrative and scientific work around importing, generating, maintaining, experimenting, monitoring, and reporting of mouse colonies. I am an up and coming academic with numerous high impact publications and several more in the pipeline. I also contribute to the scientific community by being a reviewer for peer reviewed publications for multiple journals. I have expertise in laboratory techniques such as Immunohistochemistry/Immunocytochemistry, RNA Scope and Base Scope and am proficient in mouse techniques and methodologies of collecting various mouse organs/tissue.
I am an enthusiastic and conscientious academic researcher who is actively making wider contributions to understanding the role of sex in colorectal cancer risk and susceptibility. In addition to being highly productive in a laboratory setting, I am also involved in supervision of undergraduate, post graduate and PhD students over a variety of projects in the field of colorectal cancer. Furthermore, my role as a supervisor has been appreciated by being nominated for a prize in the category of ‘Student supervision’. As a part of my professional development, I successfully applied for the Refocus Research program and learned to navigate the funding landscape within biosciences, manage difficult conversations and understand how to be resilient and recover from potential disappointments. I am working towards developing my teaching portfolio by achieving an Associate Fellowship of the Higher Education Academy. I have demonstrated a personal and institutional commitment to professionalism in learning and teaching in higher education.
Employment
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University of Edinburgh Research Fellow2013 - Present
Education
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Aston University PhD Biomedical Sciences2010 - 2013
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Newcastle University MRes. Medical and molecular biosciences2008 - 2009
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Manipal University BSc. Biotechnology2005 - 2008
Projects & Funding
Projects & funding information is unavailable.
Publications (6)
- NSUN2 mediates intestinal stem cell expansion and colorectal tumour initiation via MAPK/ERK signalling. Save
- Genetic variation at 11q23.1 confers colorectal cancer risk by dysregulation of colonic tuft cell transcriptional activator POU2AF2 Save
- Transcriptional dynamics of colorectal cancer risk associated variation at 11q23.1 correlate with tuft cell abundance and marker expression in silico. Save
- Development of Preclinical Ultrasound Imaging Techniques to Identify and Image Sentinel Lymph Nodes in a Cancerous Animal Model. Save
- Vitamin D treatment induces in vitro and ex vivo transcriptomic changes indicating anti-tumor effects. Save
- Aspirin Rescues Wnt-Driven Stem-like Phenotype in Human Intestinal Organoids and Increases the Wnt Antagonist Dickkopf-1. Save