Gopinath Krishnappa

About

Structural biology, molecular biology, Protein chemistry, chromatography & biophysical techniques, cell biology & immunology.

Employment

• National institute of mental health and neurosciences Senior researcher
  2019 - 2022
• National Institute of Mental Health and Neurosciences Senior researcher
  2015 - 2018
• Chromous Biotech (P) Ltd Team lead
  2013 - 2015
• Abexome Bioscience (P) Ltd Assistant Scientist
  2011 - 2013

Education

Education history is unavailable.

Projects & Funding

Projects & funding information is unavailable.

Publications (6)

• Structural Basis for the Essential Role of Ca2+ in the Lytic Activity of Staphylococcus aureus PlyGRCS Endolysin Targeting Methicillin-Resistant Staphylococcus aureus.
  Proteins 2024 DOI: 10.1002/prot.26777
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• Structural and biochemical insights into the bacteriophage PlyGRCS endolysin targeting methicillin‐resistant Staphylococcus aureus (MRSA) and serendipitous discovery of its interaction with a cold shock protein C (CspC)
  Protein Science 2023 DOI: 10.1002/pro.4737
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• Chlorhexidine as a Keap1-Nrf2 inhibitor: a new target for an old drug for Parkinson's disease therapy.
  Journal of biomolecular structure & dynamics 2022 DOI: 10.1080/07391102.2022.2086175
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• Structural insights into the multiple binding modes of Dimethyl Fumarate (DMF) and its analogs to the Kelch domain of Keap1.
  The FEBS journal 2020 DOI: 10.1111/febs.15485
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• Novel pyrano 1,3 oxazine based ligand inhibits the epigenetic reader hBRD2 in glioblastoma.
  The Biochemical journal 2020 DOI: 10.1042/bcj20200339
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• The Keap1-Nrf2 pathway: promising therapeutic target to counteract ROS-mediated damage in cancers and neurodegenerative diseases.
  Biophysical reviews 2016 DOI: 10.1007/s12551-016-0244-4
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