Sathish B shivachandra
National Institute Of Veterinary Epidemiology And Disease Informatics, ICAR-Indian Veterinary Research Institute, University of Agricultural Sciences, Bangalore
About
Dr. S B Shivachandra's area of research Interest include realm of Molecular Epidemiology, Pathogenesis, diagnosis and development of recombinant Vaccines and Diagnostics for Infectious Diseases of Livestock. Additionally, promotion of entrepreneurship in agriculture and allied sector.
Dr. S.B. Shivachandra's research work is predominantly based on recombinant proteins and their utility in either development of subunit vaccines or diagnostic assays for infectious diseases. Among several notable achievements, development of a novel Bacteriophage T4 based in vitro antigen display and delivery system for delivery of soluble antigens as particulate antigens to enhance the vaccine efficacy has been well established for the first time. He evaluated several bacterial and viral antigens (>50) as recombinant subunit vaccine or diagnostic reagents following assessment of their immunogenicity in laboratory animal models and immuno-diagnostic potential in various platforms such as ELISA. Several innovative methodologies were employed in production of diverse microbial antigens as recombinant fusion proteins following design and downstream processing in purification. Recently, he filed one patent for developing a kit for bluetongue. Further, his work also included development of rapid diagnostic assays based on nucleic acid and typing tools for epidemiological analysis of disease outbreaks in livestock. Overall, his work contributed for potential utility of recombinant proteins in animal health.
Employment
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National Institute Of Veterinary Epidemiology And Disease Informatics Principal Scientist2016 - 2033
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ICAR-Indian Veterinary Research Institute Senior Scientist2010 - 2015
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Karnataka Veterinary Animal and Fisheries Sciences University Assistant Professor2009 - 2010
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Catholic University of America Post Doctoral Research Associate2004 - 2008
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Indian Veterinary Research Institute Research Associate2003 - 2003
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National Institute Of Veterinary Epidemiology And Disease Informatics Principal scientist
Education
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ICAR-Indian Veterinary Research Institute PhD2000 - 2003
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ICAR-Indian Veterinary Research Institute MVSc1998 - 2000
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University of Agricultural Sciences, Bangalore BVSc1993 - 1998
Projects & Funding
Projects & funding information is unavailable.
Publications (69)
- Development and Validation of a Population Assay for the Seroprevalence of Lumpy Skin Disease Save
- Comparative evaluation of indirect-ELISAs based on native antigens of Clostridium chauvoei for the detection of blackleg-specific antibodies in cattle Save
- Comparative genome analysis of virulent strains of Bacillus anthracis causing anthrax outbreaks in animals Save
- Functional characterization of the Clostridium perfringens quadruple point mutant epsilon toxin Save
- Anti-quorum sensing and anti-biofilm activities of Pasteurella multocida strains Save
- Production of highly soluble and immuno-reactive recombinant flagellin protein of Clostridium chauvoei Save
- Phylogenetic Analysis Based on OmpA Protein Sequences of Diverse Pasteurella multocida Strains Originated from Different Animal Host Species Save
- Comparative genome analysis of Pasteurella multocida strains of porcine origin Save
- Quantifying the influence of climate, host and change in land-use patterns on occurrence of Crimean Congo Hemorrhagic Fever (CCHF) and development of spatial risk map for India Save
- Development of recombinant sialidase (NanH) protein-based Indirect-ELISA for epidemiological survey of anti-Pasteurella multocida antibodies in bovines Save