Stephan Uphoff

Employment

Employment history is unavailable.

Education

• University of Oxford Doctor of Philosophy (PhD)
  2009 - 2013
• University of Oxford Master of Science
  2008 - 2009
• Georg-August-Universität Göttingen
  2005 - 2008

Projects & Funding

Projects & funding information is unavailable.

Publications (46)

• RecA structure kinetics determine SOS dynamics and predict spontaneous cell death
  2026 DOI: 10.64898/2026.10.19.760072
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• Single-molecule imaging of DNA repair and cytoplasmic rigidification in intracellular bacteria
  2026 DOI: 10.64898/2026.09.14.751380
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• A systematic identification of resistance determinants to antisense antibiotics suggests adaptation strategies dependent on the delivery peptide
  Nature Communications 2026 DOI: 10.1038/s41467-026-76357-y
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• Replication-coupled search positions MutH for strand incision in DNA mismatch repair
  2026 DOI: 10.64898/2026.07.21.739762
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• Selective interaction of SMCHD1 with chromatin is governed by LRIF1 and SMCHD1 ATPase activity
  Nature Communications 2026 DOI: 10.1038/s41467-026-74427-9
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• Selective interaction of the protein SMCHD1 with specific chromatin regions is governed by the loading factor LRIF1 and SMCHD1 ATPase activity
  2025 DOI: 10.1101/2025.06.13.659515
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• Immobile lipopolysaccharides and outer membrane proteins differentially segregate in growing Escherichia coli
  Proceedings of the National Academy of Sciences 2025 DOI: 10.1073/pnas.2414725122
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• The master regulator OxyR orchestrates bacterial oxidative stress response genes in space and time
  Cell Systems 2024 DOI: 10.1016/j.cels.2024.10.003
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• Robust Quantification of Live-Cell Single-Molecule Tracking Data for Fluorophores with Different Photophysical Properties
  The Journal of Physical Chemistry B 2024 DOI: 10.1021/acs.jpcb.4c01454
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• A simple regulatory network coordinates a bacterial stress response in space and time
  2024 DOI: 10.1101/2024.03.07.583862
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• Chaos in a bacterial stress response
  Divya Choudhary, Kevin R. Foster, Stephan Uphoff
  Current Biology 2023 DOI: 10.1016/j.cub.2023.11.002
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• Phenotypic heterogeneity in the bacterial oxidative stress response is driven by cell-cell interactions
  Divya Choudhary, Valentine Lagage, Kevin R. Foster +1 more
  Cell Reports 2023 DOI: 10.1016/j.celrep.2023.112168
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• Adaptation delay causes a burst of mutations in bacteria responding to oxidative stress
  EMBO Reports 2023 DOI: 10.15252/embr.202255640
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• Environmental feedback drives oxidative stress response heterogeneity in bacterial populations
  2022 DOI: 10.1101/2022.09.02.506373
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• Adaptation delay causes a burst of mutations in bacteria responding to oxidative stress
  2022 DOI: 10.1101/2022.05.25.493234
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• Cellular heterogeneity in DNA alkylation repair increases population genetic plasticity
  Nucleic Acids Research 2021 DOI: 10.1093/nar/gkab1143
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• Nonrandom segregation of sister chromosomes by Escherichia coli MukBEF
  Proceedings of the National Academy of Sciences 2021 DOI: 10.1073/pnas.2022078118
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• Single-molecule imaging of LexA degradation in Escherichia coli elucidates regulatory mechanisms and heterogeneity of the SOS response
  Nature Microbiology 2021 DOI: 10.1038/s41564-021-00930-y
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• Cellular heterogeneity in DNA alkylation repair as a trade-off between cell survival and genetic plasticity
  2021 DOI: 10.1101/2021.05.24.445533
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• Pulses and delays, anticipation and memory: seeing bacterial stress responses from a single-cell perspective
  FEMS Microbiology Reviews 2020 DOI: 10.1093/femsre/fuaa022
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