Dr. Mukesh Pratap Yadav
University of Maryland, Baltimore, National Institutes of Health, Veer Bahadur Singh Purvanchal University, University of Gothenburg
0000-0002-3661-5141
About
Dr. Mukesh Pratap Yadav is a cancer biologist specializing in molecular oncology, epigenetics, and gene and cell therapy. His research focuses on understanding the mechanisms of DNA replication, epigenetic regulation, and cancer cell signaling, with the goal of developing targeted and precision-based therapeutic strategies.
His work has contributed to key areas of cancer biology, including the role of DNA modifications such as 5-hydroxymethylcytosine in leukemia progression, as well as the regulation of tumor cell behavior through Arf GTPase-mediated signaling pathways. He has also conducted foundational studies on DNA replication dynamics and genome stability using model systems such as Schizosaccharomyces pombe, advancing knowledge relevant to oncogenesis and complex diseases.
Dr. Yadav has published in leading peer-reviewed journals, including Nature Communications, Cancer Research, Nanoscale, Epigenetics, and BioTechniques, and his work is widely cited within the scientific community. He actively contributes as a peer reviewer and serves on editorial boards of international journals, reflecting his recognized expertise in cancer biology.
Currently, Dr. Yadav is working on advancing CAR-T cell therapy and gene therapy approaches, with a focus on non-invasive imaging and translational applications in cancer treatment. His recent work includes research on mesothelin (MSLN)-targeted CAR-T therapy, with a study reported in Science Advances, highlighting his contribution to next-generation immunotherapeutic strategies.
His research bridges fundamental biology and clinical translation, contributing to improved understanding of cancer mechanisms and the development of innovative therapeutic interventions.
Employment
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University of Maryland, Baltimore Staff Scientist2022 - Present
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National Institutes of Health Research fellow2021 - 2022
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University of Gothenburg Researcher2018 - 2020
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Centre for Cellular and Molecular Biology National Postdoctoral Fellow2014 - 2017
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Veer Bahadur Singh Purvanchal University Senior Research Fellow2010 - 2014
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Veer Bahadur Singh Purvanchal University UGC Research Fellow2008 - 2010
Education
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Veer Bahadur Singh Purvanchal University PhD2008 - 2014
Projects & Funding
Projects & funding information is unavailable.
Publications (17)
- Fluorescence Imaging of DMDG-ICG Across NIR-I and NIR-II Windows Using a Single-Camera System Save
- Near-infrared imaging of intraperitoneal ovarian cancer enhanced by BrCy112 in a dual mode (MR and NIR), dual-Gd nanoparticle. Save
- ARID4B: An Orchestrator from Stem Cell Fate to Carcinogenesis Save
- Tongue orthotopic xenografts to study fusion-negative rhabdomyosarcoma invasion and metastasis in live animals Save
- Chromatin Immunoprecipitation and Library Preparation: a Powerful Tool to Unravel the Epigenome Save
- The small molecule inhibitor NAV-2729 has a complex target profile including multiple ADP-ribosylation factor regulatory proteins Save
- Modulation of ASAP1 in FN-RMS cells accelerates tumor progression and metastasis as revealed by intravital microscopy Save
- The use of a novel orthotopic xenograft model of fusion negative rhabdomyosarcoma to study the effect of ASAP1 on tumor progression and metastasis Save
- HnRNPK maintains single strand RNA through controlling double-strand RNA in mammalian cells Save
- Control of cell signaling by Arf GTPases and their regulators: Focus on links to cancer and other GTPase families Save