RP
0000-0002-3908-530X About
Research Interest
Using computational tools, molecular modeling, biophysics, and analysis of sequence- structural data to address the fundamental problems in biological molecules.
Our research work focuses on
Understanding the cytosolic pattern recognition receptor in host-pathogen interaction of innate immunity and the role played by SNP, intra-inter molecular interactions play in signaling between the evolutionary conserved integrated immune response and immune disorders.
Employment
Employment history is unavailable.
Education
Education history is unavailable.
Projects & Funding
Projects & funding information is unavailable.
Publications (20)
- Molecular spotlights of deterministic sentinel pattern recognition receptors: from priming immunity to engineering specificities for robust plant resilience Save
- Phase-Dependent Transcriptional Reprogramming of Vitis vinifera During Pierce’s Disease Progression by Xylella fastidiosa Infection Save
- Exploring the modulation of phosphorylation and SUMOylation-dependent NPR1 conformational switching on immune regulators TGA3 and WRKY70 through molecular simulation Save
- Understanding a point mutation signature D54K in the caspase activation recruitment domain of NOD1 capitulating concerted immunity via atomistic simulation Save
- Essential oils from Murraya koenigii (L.) Spreng. and their phytochemicals as an environmental-friendly agent against pests of medical importance Save
- In-vitro and in-silico analysis of methanolic crude extracts of Mountain knotgrass Aerva lanta (L.) against two lepidopteran pests and non-target species Save
- Molecular simulation reveals that pathogenic mutations in BTB/ANK domains of Arabidopsis thaliana NPR1 circumscribe the EDS1-mediated immune regulation Save
- Systematic induced resistance in Solanum lycopersicum (L.) against vascular wilt pathogen (Fusarium oxysporum f. sp. lycopersici) by Citrullus colocynthis and Trichoderma viride Save
- Chemical screening and mosquitocidal activity of essential oil derived from Mikania scandens (L.) Willd. against Anopheles gambiae Giles and their non-toxicity on mosquito predators Save
- Exploring the structural significance of molecular switch mechanism alias motif phosphorylation in Wnt/β-catenin and their crucial role in triple-negative breast cancer Save
- Structural localization of pathogenic mutations in the central nucleotide-binding domain (NBD) of nucleotide-binding oligomerization domain-2 (NOD2) protein and their inference in inflammatory disorders Save
- Delineating the folding perturbations and molecular mechanisms of Thr-Ala 642 mutation in Rab-GTPase activating protein Akt substrate of 160kDa and its impact on the aetiology of Diabetes. Save
- Structural debilitation of mutation G322D associated with MSH2 and their role in triple negative breast cancer Save
- Differentially expressed gene (DEG) based protein-protein interaction (PPI) network identifies a spectrum of gene interactome, transcriptome and correlated miRNA in nondisjunction Down syndrome Save
- R516Q mutation in Melanoma differentiation-associated protein 5 (MDA5) and its pathogenic role towards rare Singleton-Merten syndrome; a signature associated molecular dynamics study Save
- A molecular simulation analysis of vitamin D targets interleukin 13 (IL13) as an alternative to mometasone in asthma Save
- Modeling and docking study of GABA-AT protein in mycobacterium tuberculosis - A computational approach Save
- Casting the critical regions in nucleotide binding oligomerization domain 2 protein: a signature mediated structural dynamics approach Save
- Expediting dynamics approach to understand the influence of 14-3-3ζ causing metastatic cancer through the interaction of YAP1 and β-TRCP Save
- Systematic prioritization of functional hotspot in RIG-1 domains using pattern based conventional molecular dynamic simulation Save