Deepika Gaur

About

I am a native of India. I obtained my Ph.D. degree from the Institute of Microbial Technology in India. My Ph.D. research focused on understanding the intricacies between the Hsp70 and Hsp90 classes of chaperones. Currently, I am a postdoc at the University of Pittsburgh. My interests include studying proteostasis and the localization of proteins in different organelles during stress.

Employment

• University of Pittsburgh Research Assistant Professor
  2026 - Present
• University of Pittsburgh Postdoctoral associate
  2023 - 2026
• University of Toledo Postdoctoral associate
  2021 - 2023
• University of Pittsburgh

Education

• Institute of Microbial Technology Ph.D.
  2012 - 2020
• Panjab University M.Sc. (Hons.)
  2009 - 2011
• Panjab University B.Sc. (Hons.)
  2006 - 2009

Projects & Funding

Projects & funding information is unavailable.

Publications (10)

• ALS mutations disrupt self-association between the ubiquilin STI1 hydrophobic groove and internal placeholder sequences
  Joan Onwunma, Saeed A. Binsabaan, S. Allen

  +4 more

  • Sachini Thanthirige
  • Deepika Gaur
  • Banumathi Sankaran
  • Matthew L. Wohlever
  The EMBO Journal 2026 DOI: 10.1038/s44318-026-00745-9
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• Lipid bilayer properties govern substrate engagement and extraction by the AAA+ ATPase Msp1
  Heidi L. Fresenius, Brian Acquaviva, Deepika Gaur

  +2 more

  • Baylee A. Smith
  • Matthew L. Wohlever
  Journal of Biological Chemistry 2025 DOI: 10.1016/j.jbc.2025.110614
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• An Msp1-Protease Chimera Captures Transient AAA+ Interactions and Unveils Ost4 Mislocalization Errors
  Deepika Gaur, Brian Acquaviva, Matthew L. Wohlever
  2025 DOI: 10.1101/2025.03.31.646376
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• A suite of pre‐assembled, <scp>pET28b</scp>‐based <scp>Golden Gate</scp> vectors for efficient protein engineering and expression
  Deepika Gaur, Matthew L. Wohlever
  Protein Science 2025 DOI: 10.1002/pro.70106
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• Energetic requirements and mechanistic plasticity in Msp1-mediated substrate extraction from lipid bilayers
  Baylee A. Smith, Deepika Gaur, Nathan D. Walker

  +2 more

  • Isabella Walter
  • Matthew L. Wohlever
  2024 DOI: 10.1101/2024.09.23.614443
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• The AAA+ protein Msp1 recognizes substrates by a hydrophobic mismatch
  2023 DOI: 10.1101/2023.07.11.548587
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• Ydj1 interaction at nucleotide-binding-domain of yeast Ssa1 impacts Hsp90 collaboration and client maturation
  Deepika Gaur, Navinder Kumar, Abhirupa Ghosh +8 more
  PLOS Genetics 2022 DOI: 10.1371/journal.pgen.1010442
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• The Yeast Hsp70 Cochaperone Ydj1 Regulates Functional Distinction of Ssa Hsp70s in the Hsp90 Chaperoning Pathway
  Deepika Gaur, Prashant R. Singh, Jyoti Guleria +3 more
  Genetics 2020 DOI: 10.1534/genetics.120.303190
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• Hsp90-Associated Immunophilin Homolog Cpr7 Is Required for the Mitotic Stability of [URE3] Prion in Saccharomyces cerevisiae
  Navinder Kumar, Deepika Gaur, Arpit Gupta

  +2 more

  • Anuradhika Puri
  • Deepak Sharma
  PLOS Genetics 2015 DOI: 10.1371/journal.pgen.1005567
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• The BAG Homology Domain of Snl1 Cures Yeast Prion [URE3] Through Regulation of Hsp70 Chaperones
  Navinder Kumar, Deepika Gaur, Daniel C. Masison

  +1 more

  • Deepak Sharma
  G3 Genes|Genomes|Genetics 2014 DOI: 10.1534/g3.113.009993
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