SK
Sally M. Khadrawy
Research areas: Biochemistry, Genetics and Molecular Biology · Molecular Biology · Protein Degradation and Inhibitors · Ubiquitin and proteasome pathways · Computational Drug Discovery Methods
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Publications (49)
- CBFβ–SMMHC in inv(16) AML: Fusion biology, RUNX1 dysregulation, and therapeutic targeting of a leukemogenic protein–protein interaction Save
- Structure-guided identification of 2-arylbenzothiazoles as disruptors of the oncogenic MTDH–SND1 protein–protein interaction Save
- Photo-activated Fenton-like degradation of Malachite Green using Fe₃O₄/g-C₃N₄ Ceramics Nanocomposites: Kinetics, Stability, and Mechanistic Insights Save
- Disrupting E3 ubiquitin ligase protein–protein interactions in cancer: chemical modalities, mechanisms, and therapeutic opportunities Save
- Discovery of 1 H-Pyrrolo[2,3-b]pyridine-3-sulfonamides as disruptors of the oncogenic MTDH-SND1 Protein-Protein interaction through integrated in silico and in vitro screening Save
- Polydatin inhibits hippocampal neurodegeneration in diabetic rats via modulation of oxidative stress and NF-kB/COX-2/IL-6 inflammatory pathway Save
- A comprehensive review on advanced synthesis approaches of MXenes and their dual role in photocatalytic degradation and antimicrobial applications Save
- Discovery of [1,2,4]triazolo[1,5-a]pyrimidine-based disruptors of the Skp2–Cks1 protein–protein interaction through integrated computational and experimental analysis Save
- Disrupting PQBP1–eEF2 protein-protein interaction: From synaptic translation to immunity and cancer Save
- From In Vitro Genotoxicity Assays to Human Biomarkers: Interpreting DNA Damage Signals in Long-Term SSRI Therapy through a Translational Neurotoxicology Lens Save
- Recent advances in indole–thiazole hybrid scaffolds: synthesis, molecular hybridization, and pharmacological potential Save
- Structure‐Based Discovery of N‐Aryl‐N′‐Heteroaryl Ureas as Disruptors of the Oncogenic MTDH–SND1 Protein–Protein Interaction: In Silico Insights and Biochemical Validation Save
- 1H-Indazole-3-Carboxylic Acid Derivatives as Disruptors of the Oncogenic MTDH–SND1 Protein–Protein Interaction: An In Silico-to-In Vitro Study Save
- The CLOCK–BMAL1 complex in circadian regulation: structure, mechanisms, and therapeutic targeting Save
- Protein-protein interaction disruption as a next-generation antithrombotic strategy Save
- Disrupting the CBFβ-SMMHC-RUNX1 oncogenic protein–protein interaction in inv(16) AML: from fusion biology to targeted therapy Save
- Enhanced Antibacterial and Photocatalytic Performance of Synergistic Graphene/Cellulose/Chitosan–Ag Nanocomposites Save
- Targeting the Elongin <scp>BC</scp> – <scp>BC</scp> ‐Box Interface: Structural Insights, Peptidic Disruptors and Emerging Small‐Molecule Strategies Save
- Disrupting the KRAS–SOS1 protein–protein interaction: mechanistic rationale for pan-KRAS pathway suppression and combination therapy Save
- Disrupting the USP1–UAF1 deubiquitinase complex: a master regulator of replication stress and frontier target in cancer therapy Save