Maurizio Cardelli

About

M. Cardelli is Staff Biologist at INRCA-IRCCS, Advanced Technology Center for Aging Research (Ancona). He is also lecturer of "Epigenetics and Advanced Molecular Biology" at the University of Camerino. His main research interest is the study of the genomic variation associated with endogenous retroelements in the human genome, and the study of its possible involvement in aging, cancer and age-related diseases. He developed new methods to study the genetic variability associated with retrotransposable elements, and contributed to analyse the genetic factors associated with human longevity and age-associated diseases. Dr. Cardelli is now responsible of the INRCA-IRCCS operative unit in the European Genmel project (started in 2015) on the genetics of melanoma, where he is conducting the whole genome assessment of somatic mutations induced by retroelement insertions in a wide collection of melanoma cases. M. Cardelli has a wide experience as collaborator in research projects Ministry of Health and E.U. ("GEHA Genetics of Healthy Aging" European Project, FP 6).
Dr. Cardelli is Member of the Editorial Board of Scientifica (Hindawi Publishing Corporation) for the section "Genomics".

Employment

• INRCA-IRCCS Staff Biologist
  2013 - Present
• INRCA-IRCCS Contract Researcher
  1999 - 2013

Education

• Università degli Studi di Pisa Degree in Biological Sciences
  1988 - 1994
• Università degli Studi di Camerino Master in Clinical and Epidemiological Research Coordinator
  ? - 2012
• Università degli Studi di Camerino Specialization in Biochemical Chemistry
  ? - 2007
• Università degli Studi di Camerino PhD in Aging and Nutrition
  ? - 2004

Projects & Funding

• GENMEL -­ Identification of genetic markers involved in development of metastases and second cancers in melanoma Ministero della Salute
  2015 - 2018

Publications (71)

• Transposable Element Dysregulation in Fetal Down Syndrome Mesenchymal Stem Cells: Insights from a Model of Premature Ageing
  International Journal of Molecular Sciences 2026 DOI: 10.3390/ijms27219747
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• Prognostic Nutritional Index, Circulating Bacterial and Viral DNA, and Neurocognitive Vulnerability in Geriatric Inpatients: A Cross-Sectional Study
  Nutrients 2026 DOI: 10.3390/nu18203387
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• Aging and Reproductive Cancers: An Integrative View on Cell-Free DNA and Transposable Elements
  Frontiers in Bioscience-Landmark 2026 DOI: 10.31083/FBL50970
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• GLO1 cg26053840 Methylation Associates with Kidney Injury and Inflammatory Markers in Hospitalized Older Adults
  Life 2026 DOI: 10.3390/life16060917
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• Gut Microbiota Changes Following Short-Term Probiotic Supplementation in Older Home Enteral Nutrition Patients
  Nutrients 2026 DOI: 10.3390/nu18061013
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• Repeatome Analysis of Plasma Circulating DNA in Patients with Cardiovascular Disease: Variation with Cell-Free DNA Integrity/Length and Clinical Parameters
  International Journal of Molecular Sciences 2025 DOI: 10.3390/ijms26146657
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• Association of HERV-K and LINE-1 hypomethylation with reduced disease-free survival in melanoma patients
  Maurizio Cardelli, Remco van Doorn, Lares Larcher +14 more
  Epigenomics 2020 DOI: 10.2217/epi-2020-0127
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• A New Robust Epigenetic Model for Forensic Age Prediction
  Journal of Forensic Sciences 2020 DOI: 10.1111/1556-4029.14460
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• Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells
  Journal of Extracellular Vesicles 2020 DOI: 10.1080/20013078.2020.1725285
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• The genomic and epigenomic evolutionary history of papillary renal cell carcinomas
  Nature Communications 2020 DOI: 10.1038/s41467-020-16546-5
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• Nutritional factors modulating alu methylation in an italian sample from the mark-age study including offspring of healthy nonagenarians
  Nutrients 2019 DOI: 10.3390/nu11122986
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• Recovery from mild Escherichia coli O157:H7 infection in young and aged C57BL/6 mice with intact flora estimated by fecal shedding, locomotor activity and grip strength
  Comparative Immunology, Microbiology and Infectious Diseases 2019 DOI: 10.1016/j.cimid.2018.12.003
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• Anti-inflammatory Activity of Tocotrienols in Age-related Pathologies: A SASPected Involvement of Cellular Senescence
  Biological Procedures Online 2018 DOI: 10.1186/s12575-018-0087-4
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• Erratum to: Telomere length and survival in primary cutaneous melanoma patients (Scientific Reports, (2018), 8, 1, (10947), 10.1038/s41598-018-29322-9)
  Scientific Reports 2018 DOI: 10.1038/s41598-018-36657-w
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• Inducers of senescence, toxic compounds, and senolytics: The multiple faces of Nrf2-activating phytochemicals in cancer adjuvant therapy
  Mediators of Inflammation 2018 DOI: 10.1155/2018/4159013
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• Measuring zinc in biological nanovesicles by multiple analytical approaches
  Journal of Trace Elements in Medicine and Biology 2018 DOI: 10.1016/j.jtemb.2018.03.010
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• Telomere length and survival in primary cutaneous melanoma patients
  P. Sivaramakrishna Rachakonda, Nalini Srinivas, Seyed Hamidreza Mahmoudpour +10 more
  Scientific Reports 2018 DOI: 10.1038/s41598-018-29322-9
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• The epigenetic alterations of endogenous retroelements in aging
  Mechanisms of Ageing and Development 2018 DOI: 10.1016/j.mad.2018.02.002
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• Implications of impaired zinc homeostasis in diabetic cardiomyopathy and nephropathy
  BioFactors 2017 DOI: 10.1002/biof.1386
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• Precision and accuracy of the new XPrecia Stride mobile coagulometer
  Thrombosis Research 2017 DOI: 10.1016/j.thromres.2017.05.032
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