Joseph A.Q. Karam

Employment

• Medical University of South Carolina Graduate Research Assistant
  2017 - 2023

Education

• Medical University of South Carolina MD
  2023 - 2027
• Medical University of South Carolina Ph.D.
  2017 - 2023

Projects & Funding

Projects & funding information is unavailable.

Publications (14)

• Arthroscopic Capsular Plication Shows Low Failure Rates and Meaningful Functional Improvement in Multidirectional Shoulder Instability With and Without Hypermobile Ehlers‐Danlos Syndrome
  Arthroscopy, Sports Medicine, and Rehabilitation 2026 DOI: 10.1002/ars2.70077
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• PCBP1 binding to single-stranded poly-cytosine motifs enhances cGAS sensing and impairs breast cancer development
  Cécile Fréreux, Joseph A. Q. Karam, Breege V. Howley +8 more
  Communications Biology 2026 DOI: 10.1038/s42003-025-09456-z
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• Mobile endoscopy in rural South Africa: outcomes of a decentralised outreach programme to improve gastrointestinal healthcare access
  BMJ Open Gastroenterology 2025 DOI: 10.1136/bmjgast-2025-002040
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• Initial Qualitative Needs Assessment of Surgical Resident Case Logging in Low- and Middle-Income Countries Across Pan-African Training Programs
  Journal of Global Surgery (ONE) 2025 DOI: 10.52648/jogs.1208
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• The RNA-binding protein PCBP1 modulates transcription by recruiting the G-quadruplex-specific helicase DHX9
  Journal of Biological Chemistry 2024 DOI: 10.1016/j.jbc.2024.107830
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• Abstract B011: Predictors of survival and cachexia in pancreatic cancer: results from the CAMPP study
  Cancer Research 2024 DOI: 10.1158/1538-7445.pancreatic24-b011
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• PRMT5-mediated arginine methylation of FXR1 is essential for RNA binding in cancer cells
  Nucleic Acids Research 2024 DOI: 10.1093/nar/gkae319
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• Abstract 7460: Characterizing the role of PCBP1 in the activation of the cGAS-STING/type I Interferon axis to promote anti-tumor immunity
  Cécile Fréreux, Paramita Chakraborty, Annamarie C. Dalton +6 more
  Cancer Research 2024 DOI: 10.1158/1538-7445.am2024-7460
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• Genomic amplifications identified by circulating tumor DNA analysis guide prognosis in metastatic castration-resistant prostate cancer
  Frontiers in Oncology 2024 DOI: 10.3389/fonc.2023.1202277
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• The ubiquitin E3 ligase ARIH1 regulates hnRNP E1 protein stability, EMT and breast cancer progression
  Oncogene 2022 DOI: 10.1038/s41388-022-02199-9
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• Heterogeneous nuclear ribonucleoprotein E1 binds polycytosine DNA and monitors genome integrity
  Life Science Alliance 2021 DOI: 10.26508/lsa.202000995
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• Co-chaperone Hsp70/Hsp90-organizing protein (Hop) is required for transposon silencing and Piwi-interacting RNA (piRNA) biogenesis.
  The Journal of biological chemistry 2017 DOI: 10.1074/jbc.C117.777730
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• MIST, a Novel Approach to Reveal Hidden Substrate Specificity in Aminoacyl-tRNA Synthetases.
  PloS one 2015 DOI: 10.1371/journal.pone.0130042
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• Hop, The Heat Shock Link between Hsp90 and the Piwi-piRNA Pathway
  MUSC Theses and Dissertations
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