Jacob Mathew

Employment

Employment history is unavailable.

Education

• National Taiwan University of Science and Technology Phd
  2021 - 2025

Projects & Funding

Projects & funding information is unavailable.

Publications (11)

• Design and synthesis of polymer nanoparticles with pH-responsive pan-HDAC inhibitor (C5) derived from norbornene block copolymers to increase C5 solubility and improve its targeted delivery to prostate cancer sites
  Journal of Enzyme Inhibition and Medicinal Chemistry 2025 DOI: 10.1080/14756366.2025.2530557
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• Embedding Diselenide Cross‐Linked Polymer Nanoparticles In Situ Using Ring‐Opening Metathesis Polymerization (ROMP) of NORBORNENE Derived Block Copolymers for ROS‐Responsive Doxorubicin (DOX) Drug Delivery
  Journal of Polymer Science 2025 DOI: 10.1002/pol.20250616
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• Olaparib-Cediranib Hybrid as Dual PARP-VEGFR3 Inhibitor Elicits Antitumor Efficacy: Rational Design, Synthesis, Biological Evaluation and Construction of a Charge Convertible pH Responsive Nanoformulation
  Mandeep Rana, N. VijayKamasewara Rao, Zih-Yao Yu +10 more
  Bioorganic Chemistry 2025 DOI: 10.1016/j.bioorg.2025.109035
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• A polycaprolactone-based nanocarrier containing thioketal linkers and charge conversion capabilities for doxorubicin delivery
  Polymer 2025 DOI: 10.1016/j.polymer.2025.128223
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• pH-responsive synthetic polymers for drug delivery applications
  Synthetic Polymers in Drug and Biotherapeutics Delivery 2025 DOI: 10.1016/b978-0-323-95233-0.00011-x
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• Rationally designed febuxostat-based hydroxamic acid and its pH-Responsive nanoformulation elicits anti-tumor activity
  Ritika Ritika, Zi-Yi Liao, Pin-Yu Chen +9 more
  European Journal of Medicinal Chemistry 2024 DOI: 10.1016/j.ejmech.2024.116866
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• Leveraging a rationally designed veliparib-based anilide eliciting anti-leukemic effects for the design of pH-responsive polymer nanoformulation
  Amandeep Thakur, Yi-Hsuan Chu, Neralla Vijayakameswara Rao +7 more
  European Journal of Medicinal Chemistry 2024 DOI: 10.1016/j.ejmech.2024.116507
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• ROS-responsive camptothecin-linked thioketal drug delivery system based on ring-closing polymerization
  Jacob Mathew, Ru-Hung, Trong‐Nghia Le

  +5 more

  • Hoang‐Phuc Pham
  • Pawan Kumar
  • Cheng‐Kang Lee
  • Raja Shunmugam
  • Neralla Vijayakameswara Rao
  European Polymer Journal 2024 DOI: 10.1016/j.eurpolymj.2023.112646
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• Small molecule tractable PARP inhibitors: Scaffold construction approaches, mechanistic insights and structure activity relationship
  Bioorganic Chemistry 2023 DOI: 10.1016/j.bioorg.2023.106893
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• Plasma‐Enabled Graphene Quantum Dot Hydrogels as Smart Anticancer Drug Nanocarriers
  Small 2023 DOI: 10.1002/smll.202206813
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• Accommodation of ring C expanded deoxyvasicinone in the HDAC inhibitory pharmacophore culminates into a tractable anti-lung cancer agent and pH-responsive nanocarrier
  European Journal of Medicinal Chemistry 2022 DOI: https://doi.org/10.1016/j.ejmech.2022.114602
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