Uma Dhiraj Kabra

About

I am a pharmaceutical chemist and researcher with expertise in medicinal chemistry, drug discovery, and mitochondrial biology. My research focuses on the design and biological evaluation of novel therapeutic agents for cancer, diabetes, and other metabolic disorders, with a particular interest in mitochondrial dynamics, targeted drug delivery, and prodrug design.

My work integrates synthetic chemistry, molecular pharmacology, and computational approaches to identify innovative therapeutic strategies. I have contributed to research on mitochondrial function, insulin secretion, and metabolic regulation, and I am actively engaged in developing targeted therapies for cancer and mitochondrial dysfunction.

Research Interests: Medicinal Chemistry, Drug Discovery, Cancer Therapeutics, Diabetes Research, Mitochondrial Biology, Prodrug Design, Molecular Modeling, Pharmacology, and Translational Medicine.

Employment

• Parul Institute of Pharmacy Assistant professor
  2020 - 2024
• Shri SPS Sanstha Shrimati Kishoritai Bhoyar College of Pharmacy Assistant Professor
  2017 - 2019
• Chandigarh College of Pharmacy Landran Lecturer
  2007 - 2009

Education

• Technical University of Munich PhD (Medicine)
  2012 - 2017
• Shri SPS Sanstha Shrimati Kishoritai Bhoyar College of Pharmacy M.Pharm
  2005 - 2007
• Shri SPS Sanstha Shrimati Kishoritai Bhoyar College of Pharmacy B.Pharm
  2001 - 2005

Projects & Funding

Projects & funding information is unavailable.

Publications (21)

• Medicinal chemistry advances of SGLT inhibitors: SAR, structural innovation, and mechanistic insights
  European Journal of Medicinal Chemistry 2026 DOI: 10.1016/j.ejmech.2026.118707
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• Design, Synthesis, Biological Evaluation, and Computational Studies of Pyrazine‐1,3,4‐Oxadiazole Analogs as Potential Antitubercular Agents
  Chemistry & Biodiversity 2025 DOI: 10.1002/cbdv.202500777
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• Repurposing FDA-approved antimalarial drugs: Mefloquine as a promising multi-targeted therapeutic for non-small cell lung cancer
  INDIAN JOURNAL OF CHEMISTRY 2025 DOI: 10.56042/IJC.V64I7.16642
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• Synthesis and biological evaluation of furan-1,3,4-oxadiazole as antitubercular, antibacterial, and antioxidant agents
  FUTURE MEDICINAL CHEMISTRY 2025 DOI: 10.1080/17568919.2025.2570972
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• Thiazole pharmacophore-based discovery of novel SGLT2 inhibitors using virtual screening, molecular docking, and molecular dynamics simulation for diabetic nephropathy
  SAR AND QSAR IN ENVIRONMENTAL RESEARCH 2025 DOI: 10.1080/1062936X.2025.2584054
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• New Quinazolinone‐Thiouracil Derivatives: Design, Synthesis, Anticancer Evaluation, and In Silico Analysis
  ChemistrySelect 2024 DOI: 10.1002/slct.202403717
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• A comprehensive review of multi-target directed ligands in the treatment of Alzheimer's disease
  BIOORGANIC CHEMISTRY 2024 DOI: 10.1016/J.BIOORG.2024.107152
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• Discovery of potential 1,2,4-triazole derivatives as aromatase inhibitors for breast cancer: pharmacophore modelling, virtual screening, docking, ADMET and MD simulation
  MOLECULAR SIMULATION 2024 DOI: 10.1080/08927022.2024.2390950
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• Molecular docking and dynamic simulation analysis of natural polyphenols for identifying potential PTP1B inhibitors for type 2 diabetes
  INDIAN JOURNAL OF CHEMISTRY 2024 DOI: 10.56042/IJC.V63I5.9396
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• Mitochondrial Dynamics and Insulin Secretion
  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2023 DOI: 10.3390/IJMS241813782
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