Hassan Abolhassani
University Hospital Bonn, Karolinska University Hospital, Karolinska Institutet
Research areas: Immunology and Microbiology · Immunology · Immunodeficiency and Autoimmune Disorders · T-cell and B-cell Immunology · Blood disorders and treatments
0000-0002-4838-0407
About
During my doctoral degrees in Medicine, PhD in Immunogenetics and Clinical immunology I have continuously focused on inborn errors in immune system disorders and mainly on antibody deficiency. Using a multidisciplinary approach, we have developed an advanced single-cell multi-omics pipeline in order to discover and validate novel immune-related gene defects. Our patients with primary immunodeficiency within our international cohort present with different infectious and non-infectious complications including autoimmunity, inflammatory disorders, allergies, and cancers. Therefore, by understanding the mechanisms underlying these diseases, we can help not only the patients and their families but also a wide variety of unsolved chronic and common disorders with high burden worldwide
Employment
- 2026 - Present
-
Karolinska Institutet Assistant Professor2021 - 2026
Education
Education history is unavailable.
Projects & Funding
Projects & funding information is unavailable.
Publications (711)
- Genotype–phenotype analysis in 333 individuals with heterozygous variants in NFKB1 Save
- A Large Multicenter Cohort of Ataxia-Telangiectasia: Clinical, Immunologic, Genetic, and Survival Outcomes. Save
- Global and regional burden of measles and vaccine coverage among children under 5 years, 1990−2023: a Global Burden of Disease Study Save
- Human inherited RORγT deficiency encompasses genetic heterogeneity, T cell deficiency, and clinical homogeneity Save
- Correction to: Cancer Trends in Inborn Errors of Immunity: A Systematic Review and Meta‑Analysis. Save
- Immunoregulatory gene GIMAP6 suppresses lethal atherosclerotic vasculopathy and ischemic heart failure Save
- Leniolisib and rapamycin in activated PI3Kδ syndrome: Retrospective European Society for Immunodeficiencies registry-based analysis. Save
- Does CVID exist in children? A genetic architecture and manifestation map derived from 7,525 patients Save
- Neurological effects of encapsulated dexamethasone sodium phosphate in children aged 6–9 years with ataxia telangiectasia (NEAT): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial Save
- Precision Oncology in Thymic Epithelial Tumors: Therapeutic Horizons and Implementation Barriers Save
- Human inherited RORγT deficiency encompasses genetic heterogeneity, T cell deficiency, and clinical homogeneity Save
- Global, regional, and national burden of tuberculosis and multidrug-resistant tuberculosis by HIV status, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023 Save
- ALPS-like Disorder Linked with STAT3 Mutation: De Novo Variant with Bicytopenia and Literature Review Save
- APOBEC2 deficiency disrupts hematopoietic lineage commitment, resulting in emergence of dual identity lymphocytes in mice and humans Save
- GPR15-guided CD8+ T regulatory cells control intestinal inflammation Save
- Global burden of enteric infectious diseases, diarrhoeal diseases, and corresponding aetiologies, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023 Save
- Correction: Thymic epithelial tumors at the crossroads of immunity, autoimmunity, and immunotherapy Save
- LRBA organizes distinct vesicular trafficking systems in distal nephron segments for water and sodium conservation Save
- Burden of 292 causes of death and life expectancy decomposition in Iran, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023 Save
- p53: from understanding its structure to advances in therapeutic targeting. Save