Ashna Nagpal
UPMC Presbyterian, Shri Mata Vaishno Devi University
Research areas: Biochemistry, Genetics and Molecular Biology · Genetics · BRCA gene mutations in cancer · Genetic Associations and Epidemiology · DNA Repair Mechanisms
About
1. I am Dr. Ashna Nagpal, I finished my PhD in Breast Cancer Genomics, DNA damage and repair pathways in breast cancer, cancer biology on 11th Nov 2020. I have 7 years of experience in the field of Cancer genomics, DDR pathways and Cancer Biology and more than 8 publications in international journals, presently working as a Post-Doctoral Associate at UPMC, USA.
2.The focal theme of my research area during my doctorate was Breast cancer biology was, DDR factor and various Reactive Oxygen species instigating Breast cancer, with expert skills in NGS (Illumina)data analysis, WES Mass-array, GWAS studies, Sanger sequencing, TaqMan Assay, rt-PCR, ELISA, microscopy, DNA damaging techniques DNA fiber assay, on the same line I have published a few papers during my doctorate research work. Presently I am studying the role of DDR proteins at single-molecular level in real time using c-trap technology.
3.I have been working presently on the DNA repair mechanisms in cancer at single molecular level using the latest q-trap technology. We have developed a new approach to visualize single molecules DNA repair proteins detecting DNA damage in real time from nuclear extracts. I am currently working to study new structures of DNA repair proteins to generate new hypotheses with our single molecule method. The laboratory training included hands-on Plasmid cloning, Cell Transfection, EMSA, Western Blotting, c-Trap, q-Trap, Bio Render, GraphPad, PyLake, Lakeview.
Employment
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UPMC Presbyterian Post-Doctoral Associate2022 - Present
Education
- 2013 - 2020
Projects & Funding
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NIH NIH Office of the Director2022 - 2028
Publications
Publications are unavailable.