Stamatios Giannoukos
ETH Zurich, Paul Scherrer Institute, University of Liverpool, National Technical University of Athens
Research areas: Chemistry · Spectroscopy · Mass Spectrometry Techniques and Applications · Advanced Chemical Sensor Technologies · Metabolomics and Mass Spectrometry Studies
About
Stamatios Giannoukos received an MSc degree in Chemical Engineering from the National Technical University of Athens (Greece) and a PhD degree in Electrical Engineering and Electronics from the University of Liverpool, (UK). He is currently a Senior Scientist/Assistant Professor at the Department of Chemistry and Applied Biosciences at the ETH Zurich. Previously he was a PSI- Marie Skłodowska-Curie Fellow at the Laboratory of Atmospheric Chemistry at the Paul Scherrer Institute in Switzerland.
He has extensive experience in ambient ionization techniques, in mass spectrometry, in volatile organic compounds (VOCs) and in the field chemical analysis (outside the lab). His current work includes the molecular investigation and characterization of the human exhaled breath metabolome in respect to nutrition (NutriExhalome). He works on animal (dairy cows and horses) health and welfare monitoring using online and offline sensors, on animal communication, and the investigation and characterization of the volatilomic and metabolomic profile of microbial communities and single cells. He focuses on real-time breath analysis using secondary electrospray ionization (SESI) high-resolution mass spectrometry (HR-MS) and investigates the effect of certain foods or nutrients on human postprandial exhalome and metabolism. He also works with tandem MS for compounds identification, develops methodologies for quantification of gas molecules and chemometric tools/strategies to handle high-dimensional data from balanced and unbalanced multifactorial designs. He has worked with HR-MS for the development and characterization of a SESI source for the on-line and real-time chemical analysis of metal particles in energy systems and in the environmental sector. Applications of this technology include air quality monitoring and the toxicological analysis of human exposure to toxic and hazardous environments. He has organized and participated in national (Inwil, Switzerland) and international field campaigns (New Delhi, India and Xian, China) to perform organic aerosol, water-soluble metal particles and source appointment studies. He has also investigated formation mechanisms of secondary aerosols and atmospheric transformation of organic aerosols in chamber experiments (at the Paul Scherrer Institute - PSI) using SESI coupled to time-of-flight (TOF) MS, and has contributed to high-frequency measurements of gaseous and particulate chemicals using a dual-phase inlet for SESI studies.
He is specialized in analytical chemistry, in the development of chemical sensing systems with emphasis in MS, ion mobility spectrometry and gas chromatography. He has contributed to the design and development of a prototype linear ion trap and to the development and commercialization of a portable dual filter quadrupole MS (VapourSense-500, Q-Technologies Ltd. - https://www.q-technologies.co.uk/vapoursense/) for the on-site detection and online monitoring of VOCs and semi-VOCs in many applications. Specifically, Giannoukos has worked extensively in the development of various MS methodologies for detecting VOCs in homeland security (drugs of abuse, explosives, CWAs), forensics, search and rescue (breath and skin volatile emissions acting as human chemical signatures, VOCs associated with dead bodies, fire events, canines training), precision agriculture (lab and in-field detection of Ochratoxin-A in grapes and corn using portable MS), environmental (toxic and hazardous industrial compounds) and nuclear applications. He has also developed apparatuses that can produce gas standards with high precision for calibration purposes and he has investigated (theoretically and experimentally) molecular communications in macroscale environments using MS as the main detection sensor.
He has acted as a consultant for several international companies and has entrepreneurial experience in the MS market. He has actively participated as a researcher or PI/co-PI in 3 EU-FP7 projects, 3 Horizon 2020 projects, an EPSRC funded project (UK), an Innovate UK and 3 Swiss projects (PSI, ENE interlaboratory collaboration, NutriExhalomics – funded by Agroscope, Von Roll). He is the author of more than 30 peer-reviewed journal publications and more than 60 conference publications.
Employment
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ETH Zurich Senior Scientist2020 - Present
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Paul Scherrer Institute Scientist2018 - 2020
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University of Liverpool University Teacher2018 - 2018
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University of Liverpool Postdoctoral Research Associate2015 - 2017
Education
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University of Liverpool Ph.D.2012 - 2015
- 2004 - 2010
Projects & Funding
Projects & funding information is unavailable.
Publications (57)
- Within-day temporal dynamics of exhaled breath features during prolonged fasting monitored by SESI-HRMS: a pilot study Save
- Noninvasive Disease Diagnostics: The Swiss Contribution Highlights to Breath Analysis Research Save
- Long-term performance monitoring of a secondary electrospray ionisation high-resolution mass spectrometry platform using a vapor generator for routine quality control Save
- Pheromone measurement using secondary electrospray ionization and portable membrane inlet mass spectrometry Save
- Temporal dynamics of exhaled breath features during prolonged fasting monitored by SESI-HR-MS: a pilot study Save
- Artificial Intelligence and Machine Learning in the Diagnosis and Prognosis of Diseases Through Breath Analysis: A Scoping Review Save
- Breathprints of the Barn: The Future of Livestock Research and Monitoring with Exhalomics Save
- Exploring exhaled breath biomarkers for lactose intolerance diagnosis: the Lactobreath pilot study protocol Save
- Challenges in the identification and quantitation in on-line breath analysis Save
- A sampling method for differentiating breath and ruminal exhaled volatile organic compounds in dairy cows using methane as a marker Save
- Systematic study of polymer gas sampling bags for offline analysis of exhaled breath Save
- Comparative analysis of feature annotation methods for SESI-HRMS in exhaled breath analysis Save
- Internal Standard Addition System for Online Breath Analysis Save
- Alternative electrolyte solutions for untargeted breath metabolomics using secondary‐electrospray ionization high‐resolution mass spectrometry Save
- Advances in secondary electrospray ionization for breath analysis and volatilomics Save
- Elucidating the Role of Ion Suppression in Secondary Electrospray Ionization Save
- Food and lifestyle impact on breath VOCs using portable mass spectrometer—pilot study across European countries Save
- Exhaled volatile fatty acids, ruminal methane emission, and their diurnal patterns in lactating dairy cows Save
- Analysis of volatile short-chain fatty acids in the gas phase using secondary electrospray ionization coupled to mass spectrometry Save
- Multiscale modeling of VOC–graphene nanostructure interactions: designing new sorbents for portable mass spectrometric applications Save