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Matthew Young
Also known as: Matt Young; Matthew J. Young; Matthew Jason Young
SIU School of Medicine
0000-0002-5109-4719
Employment
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SIU School of Medicine Tenured Associate Professor2015 - Present
Education
Education history is unavailable.
Projects & Funding
Projects & funding information is unavailable.
Publications (24)
- High-concentration MEHP triggers mtDNA depletion in undifferentiated HepaRG and C2C12 cultures and disrupts mitochondrial homeostasis in both HepaRG culture states Save
- Our current understanding of the biological impact of endometrial cancer mtDNA genome mutations and their potential use as a biomarker Save
- Heterozygous p.Y955C mutation in DNA polymerase γ leads to alterations in bioenergetics, complex I subunit expression, and mtDNA replication Save
- Identification of Somatic Mitochondrial DNA Mutations, Heteroplasmy, and Increased Levels of Catenanes in Tumor Specimens Obtained from Three Endometrial Cancer Patients Save
- A non‐radioactive DNA synthesis assay demonstrates that elements of the Sigma 1278b Mip1 mitochondrial DNA polymerase domain and C‐terminal extension facilitate robust enzyme activity Save
- The antiretroviral 2′,3′-dideoxycytidine causes mitochondrial dysfunction in proliferating and differentiated HepaRG human cell cultures Save
- Remdesivir triphosphate blocks DNA synthesis and increases exonucleolysis by the replicative mitochondrial DNA polymerase, Pol γ Save
- Analysis of Mitochondrial DNA Polymorphisms in the Human Cell Lines HepaRG and SJCRH30. Save
- Analysis of Human Mitochondrial DNA Content by Southern Blotting and Nonradioactive Probe Hybridization. Save
- Comparison of HepaRG cells following growth in proliferative and differentiated culture conditions reveals distinct bioenergetic profiles. Save