GOPICHAND GUTTI
The Ohio State University College of Pharmacy, Indian Institute of Technology BHU, Nirma University, The Tamilnadu Dr.MGR medical university, Jubilant Chemsys Ltd
0000-0002-5284-2379
About
I wish to introduce myself, Gopichand Gutti, a strong Pharmaceutical and Medicinal Chemistry research professional with a Doctor of Philosophy (Ph.D.) from Department of Pharmaceutical Engineering & Technology, Indian Institute of Technology (BHU), Varanasi, INDIA.
My Ph.D. research work involved design and development of novel chemical entities by fragment and scaffold based modern medicinal chemistry approaches. The synthesized compounds were characterized by analytical techniques (FT-NMR, FT-IR, HPLC, LC-MS/HRMS) and biologically evaluated with various in-vitro and in-vivo studies.
As an EMBO short-term fellow, I have learned basic electrophysiological measurements using the two-electrode voltage clamp technique. In this collaborative work with Prof. Michael Hollmann in the Department of Biochemistry I - Receptor Biochemistry at Ruhr University Bochum, Germany, I have evaluated GluN2B-selective NMDA receptor antagonism profiles of some new chemical entities.
Apart from this, I am having two years of industrial experience after my master’s as a Research Associate in synthesis division at Jubilant Chemsys Ltd,. India, division of Jubilant Life Sciences Ltd.
In this effort, I found myself profoundly efficient in performing both wet and moisture sensitive multistep organic reactions along with experience in handling various analytical techniques. Specialized hands-on expertise in performing biochemical assays (Enzyme inhibition studies, PAMPA-Blood brain barrier assay, Electrophysisological studies and Cell-line based studies). Excellent manuscript writing, presentation and oral communication skills, multitasking & problem solving ability, working experience under the supervision of a group leader, handling technical challenges, scientific creativity, enthusiastic in scientific and technical discussions, dedicated to work collaboratively with cross-functional as well as cross-geographic team environment.
Currently, working as a Post-doctoral researcher within the research group of Dr. Craig A. McElroy at Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, OH, USA.
My professional objective is to establish a strong career in the field of neuroscience and to strive for excellence in the field of research and development with dedication, focus, proactive approach, positive attitude, passion to utilize my knowledge and skills.
If you think we can benefit from each other's expertise, feel free to reach out at [email protected]
Employment
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The Ohio State University College of Pharmacy Post-Doctoral Researcher2020 - Present
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Indian Institute of Technology BHU Research Scholar2015 - 2020
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Jubilant Chemsys Ltd Research Associate2013 - 2015
Education
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Nirma University M.Pharmacy2011 - 2013
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The Tamilnadu Dr.MGR medical university B.Pharm2006 - 2010
Projects & Funding
Projects & funding information is unavailable.
Publications (22)
- In-silico guided design, screening, and molecular dynamic simulation studies for the identification of potential SARS-CoV-2 main protease inhibitors for the targeted treatment of COVID-19 Save
- Centella asiatica improves memory and executive function in middle-aged rats by controlling oxidative stress and cholinergic transmission Save
- Development of homology model, docking protocol and Machine-Learning based scoring functions for identification of Equus caballus's butyrylcholinesterase inhibitors Save
- Improved machine learning scoring functions for identification of Electrophorus electricus's acetylcholinesterase inhibitors Save
- A Systematic Review of carbohydrate-based Bioactive Molecules for Alzheimer’s Disease Save
- Systematic review on role of structure based drug design (SBDD) in the identification of anti-viral leads against SARS-Cov-2 Save
- Anthraquinone: a Promising Scaffold for the Discovery and Development of Therapeutic Agents in Cancer Therapy Save
- Anthraquinone: a promising scaffold for the discovery and development of therapeutic agents in cancer therapy Save
- Structure-based screening and molecular dynamics simulation studies for the identification of potential acetylcholinesterase inhibitors Save
- Rational approaches of drug design for the development of selective estrogen receptor modulators (SERMs), implicated in breast cancer Save