SS

sibani Sen Chakraborty

West Bengal State University, Bose Institute, University of Florida, Saha Institute of Nuclear Physics

ORCID iD 0000-0002-5309-8481

About

My research focuses on the exploration of beneficial microorganisms from harsh and extreme environments, with particular emphasis on the identification and characterization of thermostable enzymes for industrial applications. My work aims to discover robust microbial biocatalysts with potential use in diverse biotechnological processes.

In addition, I employ bioinformatics and structural biology approaches to investigate the structure–function relationships of industrially important enzymes, particularly proteases and lipases. By integrating computational analyses with experimental studies, my research seeks to understand the molecular determinants of enzyme stability, specificity, and catalytic efficiency, thereby facilitating the development of improved enzymes for industrial and biotechnological applications.

Employment

  • West Bengal State University Associate Professor
    2009 - Present

Education

  • Bose Institute Ph.D.
  • University of Florida Postdoctoral fellow
  • Saha Institute of Nuclear Physics Research Associate

Projects & Funding

Projects & funding information is unavailable.

Publications (19)

  • Abstract Book and Proceedings of One Day National Seminar CHALLENGES IN MICROBIOLOGY: DETECTION, PREVENTION & BENEFICIAL UTILIZATION 2026
    Challenges in Microbiology: Detection, Prevention and Beneficial Utilisation 2026 DOI: 10.5281/ZENODO.21793255
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  • A statistical insight to exploration of medicinal wastewater as a source of thermostable lipase-producing microorganisms
    PLOS ONE 2025 DOI: 10.1371/journal.pone.0319023
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  • Crystallization and preliminary X-ray analysis of the aspartic protease plasmepsin 4 from the malarial parasite Plasmodium malariae.
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  • Targeting the Trypanothione Reductase of Tissue-Residing Leishmania in Hosts' Reticuloendothelial System: A Flexible Water-Soluble Ferrocenylquinoline-Based Preclinical Drug Candidate.
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  • Successful Therapy of Murine Visceral Leishmaniasis with Astrakurkurone, a Triterpene Isolated from the Mushroom Astraeus hygrometricus, Involves the Induction of Protective Cell-Mediated Immunity and TLR9.
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  • Structural insights into the substrate specificity and activity of ervatamins, the papain-like cysteine proteases from a tropical plant, Ervatamia coronaria.
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  • Serratia sp. scl1: isolation of a novel thermostable lipase producing microorganism which holds industrial importance.
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  • Pharmacophore modeling coupled with molecular dynamic simulation approach to identify new leads for meprin-β metalloprotease.
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  • PLVAP and GKN3 Are Two Critical Host Cell Receptors Which Facilitate Japanese Encephalitis Virus Entry Into Neurons.
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  • Insights from Analysis of Binding Sites of Human Meprins: Screening of Inhibitors by Molecular Dynamics Simulation Study.
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