FC
Fay Cooper
University of Sheffield, The Francis Crick Institute, MRC Human Genetics Unit
Research areas: Biochemistry, Genetics and Molecular Biology · Molecular Biology · Developmental Biology and Gene Regulation · Autophagy in Disease and Therapy · Zebrafish Biomedical Research Applications
Employment
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University of Sheffield Research Associate2021 - Present
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The Francis Crick Institute Postdoctoral training fellow2016 - 2021
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MRC Human Genetics Unit PhD student2011 - 2015
Education
Education history is unavailable.
Projects & Funding
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Development of a human pluripotent stem cell-based therapy against Hirschsprung disease Medical Research Council2026 - 2029
Publications (13)
- Notch signalling governs human enteric nervous system progenitor dynamics Save
- Functional and molecular rescue of aganglionic colon by human enteric nervous system progenitor transplantation in Hirschsprung disease Save
- Human enteric nervous system progenitor transplantation improves functional responses in Hirschsprung disease patient-derived tissue. Save
- Zebrafish reveal new roles for Fam83f in hatching and the DNA damage-mediated autophagic response Save
- Notch signalling influences cell fate decisions and HOX gene induction in axial progenitors Save
- Notch signalling influences cell fate decisions and HOX gene induction in axial progenitors Save
- Generation of FOUR iPSC lines (CRICKi004-A; CRICKi005-A; CRICKi006-A, CRICKi007-A) from Spinal muscle atrophy patients with lower extremity dominant (SMALED) phenotype. Save
- Towards clinical applications of in vitro-derived axial progenitors. Save
- Rostrocaudal patterning and neural crest differentiation of human pre-neural spinal cord progenitors in vitro Save
- Shaping axial identity during human pluripotent stem cell differentiation to neural crest cells Save
- Rostrocaudal patterning and neural crest differentiation of human pre-neural spinal cord progenitors in vitro Save
- PAWS1 controls Wnt signalling through association with casein kinase 1α Save
- Mutations in CDC45, Encoding an Essential Component of the Pre-initiation Complex, Cause Meier-Gorlin Syndrome and Craniosynostosis Save