Amit Verma
Also known as: Amit K. Verma
Albert Einstein College of Medicine, UT Southwestern, Northwestern University, University of Illinois, Northwestern University Medical School, University of Chicago
About
I have been involved in study of pathogenesis of myeloid malignancies such as MDS and AML. I have elucidated the critical role of signaling pathways (p38 MAP kinase, TGF-beta, smad2/3, IRAK, PRMT5, Glutaminase and others) activation in CH, MDS, AML and this work has directly led to the therapeutic targeting as these pathways in clinical trials in MDS/AML (Nat Cell Bio 2019, JCI 2018, Blood 2015, 2011, JCO 2020, NEJM 2020, Nat Cancer 2024, SciTM 2025, JCI 2025, Can Disc, 2025). I was on the team to first define stem cell alterations in MDS/AML and our work has optimized flow-cytometric and molecular assays to work with small numbers of primary samples (JCI 2024, Nat Med, 2018; JCI 2014, Blood 2012). Our lab has also developed genome wide assays for DNA methylation and hydroxymethylation and used them in a variety of tumor models including pancreatic cancer (Can Disc, 2019; Elife, 2019; JCI, 2018; Gen Res, 2017, NAR 2016, Nat Immunol 2015). I have also conducted clinical studies in hematologic malignancies (Blood 2025, Cancer Cell 2021, Can Disc, 2020; JAMA Onc 2018, Nat Med 2022) that have also studied the effects of COVID-19 and environmental exposures on outcomes and pathogenesis. I have also been actively engaged in early phase clinical trials that are investigating novel agents for CH, MDS and AML.
Employment
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Albert Einstein College of Medicine Chairman2025 - Present
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Albert Einstein College of Medicine Associate Director2021 - Present
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Albert Einstein College of Medicine Professor, Medicine, Oncology2014 - Present
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Albert Einstein College of Medicine Division Director2013 - 2025
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Albert Einstein College of Medicine Associate Prof., Medicine, Oncology2009 - 2014
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Albert Einstein College of Medicine Assistant Professor2005 - 2009
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UT Southwestern Assistant Professor2003 - 2005
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Northwestern University Medical School Fellow2002 - 2003
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University of Illinois Medical School Fellow1999 - 2002
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University of Illinois Medical School Residency1996 - 1999
Education
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Northwestern University Fellow? - 2003
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University of Illinois Fellow? - 2002
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University of Chicago Resident? - 1999
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All India Institute of Medical Sciences Foreign-Bachelor of Medicine and Surgery? - 1995
Projects & Funding
Projects & funding information is unavailable.
Publications (272)
- Data from Rapid Transcription Dynamics Confers Cytarabine Resistance in Acute Myeloid Leukemia Save
- Key Resources Table S1 from Rapid Transcription Dynamics Confers Cytarabine Resistance in Acute Myeloid Leukemia Save
- Rapid Transcription Dynamics Confers Cytarabine Resistance in Acute Myeloid Leukemia Save
- Supplementary Figures S1-S9 from Rapid Transcription Dynamics Confers Cytarabine Resistance in Acute Myeloid Leukemia Save
- Supplementary Tables S1-S6 from Rapid Transcription Dynamics Confers Cytarabine Resistance in Acute Myeloid Leukemia Save
- ANTIBODIES TARGETING S100A8/A9 HETEROOLIGOMERS AND USES THEREOF. Save
- Elevated Clonal Hematopoiesis in 9/11 First Responders Has Distinct Age-related Patterns and Relies on IL1RAP for Clonal Expansion. Save
- Small molecule OPA1 inhibitors reverse mitochondrial adaptations to overcome therapy resistance in acute myeloid leukemia Save
- Metronomic low-dose regimen of decitabine and venetoclax is safe and reduces monocyte burden in chronic myelomonocytic leukemia. Save
- Cigarette smoking is associated with worse prognosis in myelodysplastic syndromes and hematopoietic alterations in murine models. Save