Ajay Sarawagi

About

I investigate the molecular mechanisms of fast-acting antidepressants such as ketamine and electroconvulsive therapy (ECT). I utilize mouse models to simulate depression traits and to understand the influence of ketamine or ECT. I employ NMR spectroscopy to study brain metabolism changes and proteomics to examine how proteins are impacted during disease conditions. This approach deepens our understanding of depression and potential interventions.

Employment

• Centre for Cellular and Molecular Biology Graduate Student
  2019 - Present

Education

• Bundelkhand University Master of Zoology
  2016 - 2018

Projects & Funding

Projects & funding information is unavailable.

Publications (5)

• Biphasic effect of nicotine on glutamatergic activity in male mouse brain
  British Journal of Pharmacology 2026 DOI: 10.1111/bph.70242
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• Repeated Electroconvulsive Shock Transiently Affects Cognition and Neurometabolism in Mice.
  The journal of ECT 2025 DOI: 10.1097/yct.0000000000001166
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• Impacts of Electroconvulsive Therapy on the Neurometabolic Activity in a Mice Model of Depression: An Ex Vivo 1H-[13C]-NMR Spectroscopy Study
  Neuroglia 2024 DOI: 10.3390/neuroglia5030021
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• Astroglial Pathology in Major Depressive Disorders: Metabolic and Molecular Aspects
  Glial Biology: Role of Glia in Health and Disease 2022
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• Glutamate and GABA Homeostasis and Neurometabolism in Major Depressive Disorder.
  Frontiers in psychiatry 2021 DOI: 10.3389/fpsyt.2021.637863
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