JR

Jagadeesh Rao

IGC Pharma Inc., NIDA, NIH, University of Illinois at Chicago, National Institute of Mental Health and Neurosciences, NIA- NIH

ORCID iD 0000-0002-5476-8512

About

1. Brain metabolism of nutritionally essential polyunsaturated fatty acids depends on both the diet and the liver SI Rapoport, JS Rao, M Igarashi Prostaglandins, Leukotrienes and Essential Fatty Acids 77 (5-6), 251-261
2. Increased excitotoxicity and neuroinflammatory markers in postmortem frontal cortex from bipolar disorder patients JS Rao, GJ Harry, SI Rapoport, HW Kim Molecular psychiatry 15 (4), 384-392
3. Epigenetic modifications in frontal cortex from Alzheimer's disease and bipolar disorder patients JS Rao, VL Keleshian, S Klein, SI Rapoport Translational psychiatry 2 (7), e132-e132
4. Neuroinflammation and synaptic loss JS Rao, M Kellom, HW Kim, SI Rapoport, EA Reese Neurochemical research 37, 903-910.
5. Dietary n-3 PUFA deprivation alters expression of enzymes of the arachidonic and docosahexaenoic acid cascades in rat frontal cortexJS Rao, RN Ertley, JC DeMar, SI Rapoport, RP Bazinet, HJ Lee Molecular psychiatry 12 (2), 151-157
6. Altered expression of apoptotic factors and synaptic markers in postmortem brain from bipolar disorder patients HW Kim, SI Rapoport, JS Rao Neurobiology of disease 37 (3), 596-603
7. Abnormal expression and functional characteristics of cyclic adenosine monophosphate response element binding protein in postmortem brain of suicide subjects Y Dwivedi, JS Rao, HS Rizavi, J Kotowski, RR Conley, RC Roberts, ... Archives of general psychiatry 60 (3), 273-282
8. Bipolar disorder and mechanisms of action of mood stabilizers SI Rapoport, M Basselin, HW Kim, JS Rao Brain research reviews 61 (2), 185-209
9. Disturbed choline plasmalogen and phospholipid fatty acid concentrations in Alzheimer's disease prefrontal cortex M Igarashi, K Ma, F Gao, HW Kim, SI Rapoport, JS Rao Journal of Alzheimer's disease 24 (3), 507-517.
10. Mode of action of mood stabilizers: is the arachidonic acid cascade a common target? JS Rao, HJ Lee, SI Rapoport, RP Bazinet Molecular psychiatry 13 (6), 585-596
11. Chronic carbamazepine decreases the incorporation rate and turnover of arachidonic acid but not docosahexaenoic acid in brain phospholipids of the unanesthetized rat: relevance …RP Bazinet, JS Rao, L Chang, SI Rapoport, HJ Lee Biological psychiatry 59 (5), 401-407
12. Chronic administration of mood stabilizers upregulates BDNF and bcl-2 expression levels in rat frontal cortex YC Chang, SI Rapoport, JS Rao Neurochemical research 34,
13. Brain lipid concentrations in bipolar disorder M Igarashi, K Ma, F Gao, HW Kim, D Greenstein, SI Rapoport, JS Rao Journal of psychiatric research 44 (3), 177-182
14. Altered fatty acid concentrations in prefrontal cortex of schizophrenic patients AY Taha, Y Cheon, K Ma, SI Rapoport, JS Rao
Journal of psychiatric research 47 (5), 636-643.
15. Chronic NMDA administration increases neuroinflammatory markers in rat frontal cortex: cross-talk between excitotoxicity and neuroinflammation
YC Chang, HW Kim, SI Rapoport, JS Rao Neurochemical research 33, 2318-2323
16. Chronic treatment of rats with sodium valproate downregulates frontal cortex NF‐κB DNA binding activity and COX‐2 mRNA1
JS Rao, RP Bazinet, SI Rapoport, HJ Lee Bipolar disorders 9 (5), 513-520
17. Protein kinase C and phospholipase C activity and expression of their specific isozymes is decreased and expression of MARCKS is increased in platelets of bipolar but not in … GN Pandey, Y Dwivedi, J SridharaRao, X Ren, PG Janicak, R Sharma Neuropsychopharmacology 26 (2), 216-228
18. Regulation of rat brain polyunsaturated fatty acid (PUFA) metabolism during graded dietary n-3 PUFA deprivation HW Kim, JS Rao, SI Rapoport, M Igarashi Prostaglandins, leukotrienes and essential fatty acids 85 (6), 361-368
19. Chronic valproate does not alter the kinetics of docosahexaenoic acid within brain phospholipids of the unanesthetized rat RP Bazinet, JS Rao, L Chang, SI Rapoport, HJ Lee Psychopharmacology 182, 180-185
20. Mood-stabilizers target the brain arachidonic acid cascade JS Rao, SI Rapoport Current molecular pharmacology 2 (2), 207-214
21. Dietary n-6 PUFA deprivation downregulates arachidonate but upregulates docosahexaenoate metabolizing enzymes in rat brain HW Kim, JS Rao, SI Rapoport, M Igarashi Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …
22. Chronic olanzapine treatment decreases arachidonic acid turnover and prostaglandin E2 concentration in rat brain Y Cheon, JY Park, HR Modi, HW Kim, HJ Lee, L Chang, JS Rao, ...Journal of neurochemistry 119 (2), 364-376
23. Coordinated gene expression of neuroinflammatory and cell signaling markers in dorsolateral prefrontal cortex during human brain development and aging CT Primiani, VH Ryan, JS Rao, MC Cam, K Ahn, HR Modi, SI Rapoport PLoS One 9 (10), e110972
24. Is schizophrenia a neurodegenerative disease? Evidence from age-related decline of brain-derived neurotrophic factor in the brains of schizophrenia patients and matched J Rao, J Chiappelli, P Kochunov, WT Regenold, SI Rapoport, LE Hong. Neurodegenerative Diseases 15 (1), 38-44.

Employment

  • IGC Pharma Inc. Principal Scientist
    2017 - Present
  • NIDA, NIH Scientific Review Officer
    2014 - 2017
  • NIA- NIH Staff Scientist
    2007 - 2014

Education

  • University of Illinois at Chicago Post Doctoral
    1999 - 2001
  • National Institute of Mental Health and Neurosciences PhD
    1994 - 1998

Projects & Funding

Projects & funding information is unavailable.

Publications (45)