Amit

About

My research is focused on the development of novel antibiotics/anti-infectives against infectious diseases. I am involved in development of novel antibiotics/antibacterials that work against difficult to treat, drug resistant bacteria like Mycobacterium tuberculosis (M. tuberculosis) and nontuberculous mycobacteria (NTM) such as M. abscessus and M. avium including high priority ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species).


Email: [email protected]

https://www.linkedin.com/in/amit-kaushik-821aa8112/

https://publons.com/researcher/1612837/amit-kaushik/

https://www.ncbi.nlm.nih.gov/myncbi/1Xutbn6H6ttQ5/bibliography/public/

Employment

• Johns Hopkins School of Medicine Researcher
  2013 - Present

Education

• All India Institute of Medical Sciences PhD
  2006 - 2012

Projects & Funding

Projects & funding information is unavailable.

Publications (33)

• Structure-Activity Relationship of Penem Antibiotic Side Chains Used against Mycobacteria Reveals Highly Active Compounds.
  ACS infectious diseases 2022 9 citations DOI: 10.1021/acsinfecdis.2c00229
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• The Novel Oxazolidinone TBI-223 Is Effective in Three Preclinical Mouse Models of Methicillin-Resistant Staphylococcus aureus Infection.
  Microbiology spectrum 2022 16 citations DOI: 10.1128/spectrum.02451-21
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• Efficacy of Long-Acting Bedaquiline Regimens in a Mouse Model of Tuberculosis Preventive Therapy.
  American journal of respiratory and critical care medicine 2022 20 citations DOI: 10.1164/rccm.202012-4541oc
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• 2D-DIGE based urinary proteomics and functional enrichment studies to reveal novel Mycobacterium tuberculosis and human protein biomarker candidates for pulmonary tuberculosis.
  Biochemical and biophysical research communications 2022 6 citations DOI: 10.1016/j.bbrc.2022.06.021
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• In Vitro Activity of Bedaquiline and Imipenem against Actively Growing, Nutrient-Starved, and Intracellular Mycobacterium abscessus.
  Antimicrobial agents and chemotherapy 2021 9 citations DOI: 10.1128/aac.01545-21
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• In vitro activity of bedaquiline and imipenem against actively growing, nutrient-starved, and intracellular Mycobacterium abscessus
  2021 0 citations DOI: 10.1101/2021.08.06.455495
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• Assessment of carbapenems in a mouse model of Mycobacterium tuberculosis infection.
  PloS one 2021 2 citations DOI: 10.1371/journal.pone.0249841
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• Development of a penem antibiotic against Mycobacteroides abscessus.
  Communications biology 2020 20 citations DOI: 10.1038/s42003-020-01475-2
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• N-Trifluoromethylthiolated Sulfonimidamides and Sulfoximines: Anti-microbial, Anti-mycobacterial, and Cytotoxic Activity.
  ACS medicinal chemistry letters 2019 42 citations DOI: 10.1021/acsmedchemlett.9b00285
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• New β-Lactamase Inhibitors Nacubactam and Zidebactam Improve the In Vitro Activity of β-Lactam Antibiotics against Mycobacterium abscessus Complex Clinical Isolates
  Antimicrobial Agents and Chemotherapy 2019 32 citations DOI: 10.1128/AAC.00733-19
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