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Rosanna Squitti

IRCCS Centro San Giovanni di Dio Fatebenefratelli, Università degli Studi eCampus, Sapienza University of Rome, Ospedale Isola Tiberina -Gemelli Isola

Research areas: Nursing · Nutrition and Dietetics · Trace Elements in Health · Alzheimer's disease research and treatments · Dementia and Cognitive Impairment Research

ORCID iD 0000-0002-5624-1140
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About

Rosanna Squitti, PhD, is a biologist and researcher in General Biochemistry (RTT) at eCampus University (Italy), with a long-standing focus on metal homeostasis and its role in human disease.
She received her PhD in Cellular and Developmental Biology from Sapienza University of Rome and completed postdoctoral training at the University of Liverpool (UK). Over the past two decades, she has held research and leadership positions across major Italian research institutions, including Fatebenefratelli Hospital (Rome) and IRCCS Fatebenefratelli (Brescia), as well as academic roles at Campus Bio-Medico University and international appointments as Visiting Professor at the University of Miami (USA).
Dr. Squitti has significantly contributed to the understanding of copper dysregulation in Alzheimer’s disease, being among the first to demonstrate that non-ceruloplasmin (“free” or exchangeable) copper is a systemic risk factor associated with disease progression and clinical outcomes. Her work has further identified ATP7B as a susceptibility gene and supported the existence of a copper-related biological subtype of Alzheimer’s disease, opening new perspectives in biomarker-driven stratification and precision medicine.
Her research integrates biochemical, genetic, and neurophysiological approaches, including metallomics, EEG-based brain activity, and systemic biomarkers, with recent extensions toward psychiatric disorders and colorectal cancer.
In parallel to her academic career, she has been actively involved in translational and industrial research, serving as Research Director and Head of R&D at IGEA Pharma, where she contributed to the development of diagnostic methods and intellectual property in the field of copper measurement and metabolism (6 patents). She has experience in clinical trial design and regulatory processes (AIFA, ethics committees), bridging basic science with clinical application.
Dr. Squitti is author of over 170 peer-reviewed publications, with an h-index of ~50 (Scopus), and has been included in the Stanford/Elsevier World’s Top 2% Scientists ranking (2022–2025). She serves on the editorial boards of several international journals, including Current Alzheimer Research, PLOS ONE, Biomolecules, and International Journal of Molecular Sciences.
Her current research focuses on systemic biological susceptibility and the role of metal dyshomeostasis as a cross-domain determinant of disease vulnerability.

Employment

  • eCampus University Researcher (RTT) in General Biochemistry
    2024 - 2030
  • Ospedale Isola Tiberina -Gemelli Isola Ricercatore collaboratore, PhD
    2023 - 2026
  • IRCCS Centro San Giovanni di Dio Fatebenefratelli Ricercatore collaboratore, PhD
    2016 - Present
  • Ospedale Generale "San Giovanni Calibita" Fatebenefratelli , Roma Biologo, contratto tempo indeterminato
    2014 - 2022
  • A.Fa.R. Ass. Fatebenfratelli per la ricerca biomedica e sanitaria Researcher
    2004 - 2014
  • A.Fa.R. Ass. Fatebenfratelli per la ricerca biomedica e sanitaria felloship
    1999 - 2004

Education

Projects & Funding

Projects & funding information is unavailable.

Publications (157)