Hannah Long

Employment

• University of Edinburgh Programme Leader Track Group Leader
  2021 - Present
• Stanford University Postdoctoral Researcher
  2014 - 2021
• University of Oxford Postdoctoral Research Associate
  2013 - 2014

Education

• University of Oxford DPhil in Chromosome and Developmental Biology
  2009 - 2013
• University of Cambridge Natural Sciences BA (Hons)
  2006 - 2009

Projects & Funding

Projects & funding information is unavailable.

Publications (21)

• Mechanisms underlying disease-causing variants in promoters and enhancers
  Nature Genetics 2026 DOI: 10.1038/s41588-026-02743-3
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• Array-CNCC: precise aggregation and arrayed plating facilitate quantitative phenotyping of human cranial neural crest cells and craniofacial disease modelling
  2026 DOI: 10.64898/2026.01.18.696654
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• Neanderthal-derived variants increase SOX9 enhancer activity in craniofacial progenitors that shape jaw development
  Development 2025 DOI: 10.1242/dev.204779
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• Neanderthal-derived variants shape craniofacial enhancer activity at a human disease locus
  2024 DOI: 10.1101/2024.09.24.614243
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• Topology regulatory elements: From shaping genome architecture to gene regulation
  Current Opinion in Structural Biology 2023 DOI: 10.1016/j.sbi.2023.102723
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• Structural elements promote architectural stripe formation and facilitate ultra-long-range gene regulation at a human disease locus.
  Molecular cell 2023 DOI: 10.1016/j.molcel.2023.03.009
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• Loss of Extreme Long-Range Enhancers in Human Neural Crest Drives a Craniofacial Disorder.
  Hannah K. Long, Marco Osterwalder, Ian C. Welsh +19 more
  Cell stem cell 2020 DOI: 10.1016/j.stem.2020.09.001
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• FaceBase 3: analytical tools and FAIR resources for craniofacial and dental research.
  Development (Cambridge, England) 2020 DOI: 10.1242/dev.191213
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• Single Amino Acid Change Underlies Distinct Roles of H2A.Z Subtypes in Human Syndrome.
  Cell 2019 DOI: 10.1016/j.cell.2019.08.002
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• The Spatiotemporal Pattern and Intensity of p53 Activation Dictates Phenotypic Diversity in p53-Driven Developmental Syndromes.
  Developmental cell 2019 DOI: 10.1016/j.devcel.2019.05.015
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• Biochemical Identification of Nonmethylated DNA by BioCAP-Seq.
  Methods in molecular biology (Clifton, N.J.) 2018 DOI: 10.1007/978-1-4939-7768-0_2
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• The SET1 Complex Selects Actively Transcribed Target Genes via Multivalent Interaction with CpG Island Chromatin.
  Cell reports 2017 DOI: 10.1016/j.celrep.2017.08.030
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• Ever-Changing Landscapes: Transcriptional Enhancers in Development and Evolution.
  2016 DOI: 10.1016/j.cell.2016.09.018
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• Successful transmission and transcriptional deployment of a human chromosome via mouse male meiosis.
  2016 DOI: 10.7554/elife.20235
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• Protection of CpG islands from DNA methylation is DNA-encoded and evolutionarily conserved.
  2016
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• Variant PRC1 Complex-Dependent H2A Ubiquitylation Drives PRC2 Recruitment and Polycomb Domain Formation.
  2014 DOI: 10.1016/j.cell.2014.05.004
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• ZF-CxxC domain-containing proteins, CpG islands and the chromatin connection.
  2013 DOI: 10.1042/BST20130028
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• Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates.
  2013 DOI: 10.7554/eLife.00348
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• Bio-CAP: a versatile and highly sensitive technique to purify and characterise regions of non-methylated DNA.
  2012 DOI: 10.1093/nar/gkr1207
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• KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands.
  2012 DOI: 10.7554/eLife.00205
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