Amit Kumar

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Publications (9)

• Atropisomerism Observed in Galactose-Based Monosaccharide Inhibitors of Galectin-3 Comprising 2-Methyl-4-phenyl-2,4-dihydro-3 H-1,2,4-triazole-3-thione.
  Journal of medicinal chemistry 2024 DOI: 10.1021/acs.jmedchem.4c01008
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• Comparative kinetic analysis of ascorbate (Vitamin-C) recycling dehydroascorbate reductases from plants and humans
  Biochemical and Biophysical Research Communications 2022 DOI: 10.1016/j.bbrc.2021.12.103
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• Molecular mechanism of interspecies differences in the binding affinity of TD139 to Galectin-3
  Glycobiology 2021 DOI: 10.1093/glycob/cwab072
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• Dual avatars of E. coli grxB encoded Glutaredoxin 2 perform ascorbate recycling and ion channel activities
  2021 DOI: 10.1101/2021.08.28.458008
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• Comparative kinetic analysis of ascorbate (Vitamin-C) recycling dehydroascorbate reductases from plant and human
  2021 DOI: 10.1101/2021.08.28.458007
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• Synthesis, Structure–Activity Relationships, and In Vivo Evaluation of Novel Tetrahydropyran-Based Thiodisaccharide Mimics as Galectin-3 Inhibitors
  Journal of Medicinal Chemistry 2021 DOI: 10.1021/acs.jmedchem.0c02001
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• Discovery of BMS-986144, a Third-Generation, Pan-Genotype NS3/4A Protease Inhibitor for the Treatment of Hepatitis C Virus Infection
  Journal of Medicinal Chemistry 2020 DOI: 10.1021/acs.jmedchem.0c01296
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• Non-native ligands define the active site of Pennisetum glaucum (L.) R. Br dehydroascorbate reductase
  Biochemical and Biophysical Research Communications 2016 DOI: 10.1016/j.bbrc.2016.04.031
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• Structure of the central RNA recognition motif of human TIA-1 at 1.95Å resolution
  Biochemical and Biophysical Research Communications 2008 DOI: 10.1016/j.bbrc.2008.01.027
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