0000-0002-5759-1775 About
Dr. Gupta obtained his graduate (Ph.D) degree from the Jamia Millia Islamia & co-institutes G.B.Pant, Hospitals and Institute of Genomics and Integrative Biology (IGIB), Delhi, focused on Identification of differentially expressed proteins in non-alcoholic fatty liver disease (NAFLD) - Proteomic and Genomic approaches to understand disease pathogenesis and progression. Dr. Gupta has over 12 years of postdoctoral Fellow working at many reputed research institutions including INSERM, Paris (France), Cincinnati University (USA) and ILBS (India). In INSERM, he used MAGL knockout mice to address: 1) monoacylglycerol lipase (MAGL) as a novel immunometabolic target in alcoholic\ non-alcoholic fatty liver disease. 2) Development and characterization of MAGL- and ATG5-deficient T cell-specific knockout mice. 3) A profibrotic role of mucosa-associated invariant T cells in liver disease. In Cincinnati, he studied the pathophysiology of steatohepatitis progression in augmented liver regeneration (ALR), a knockout mouse model for liver disease. Before joining to Artemis hospitals, Dr. Gupta also worked in ILBS on a) The DBT funded project based on early prediction of interferon response in her hepatitis C virus-infected patients using pharmacogenomics tools. b) The proteomic profile of patients with severe liver disease upon albumin transfusion in liver regeneration, and the role of cannabinoid receptors in liver disease. He is trained at IIT, Delhi in the research focused on 3D bioprinting of full-length skin, aging skin, in-vitro 3D models of human skin and hair follicle regeneration, liver scaffolds and their applications in the biomedical field.
Employment
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Artemis Hospitals Principal Research Scientist, F2023 - Present
Education
Education history is unavailable.
Projects & Funding
Projects & funding information is unavailable.
Publications (16)
- In vivo protein half-life analysis identifies the SREBF1-SLC27a5 axis governs antioxidant response in preclinical alcoholic rat model Save
- Circulating bacterial peptides and linked metabolomic signatures are indicative of early mortality in pediatric cirrhosis Save
- Early hepatic proteomic signatures reveal metabolic changes in high-fat-induced obesity in rats Save
- Biomolecular map of albumin identifies signatures of severity and early mortality in acute liver failure Save
- Circulating bacterial peptides and linked metabolomic signatures are indicative of early mortality in Paediatric Cirrhosis Save
- Hyperoxidized Albumin Modulates Platelets and Promotes Inflammation Through CD36 Receptor in Severe Alcoholic Hepatitis Save
- Direct 3D bioprinted full-thickness skin constructs recapitulate regulatory signaling pathways and physiology of human skin Save
- Dysregulated Lipid Transport Proteins Correlate With Pathogenesis and Outcome in Severe Alcoholic Hepatitis Save
- Multifunctional finishing of cellulosic fabric via facile, rapid in-situ green synthesis of AgNPs using pomegranate peel extract biomolecules Save
- Establishment of an in vitro organoid model of dermal papilla of human hair follicle Save