Professor Rizwanul Haque
Central University of South Bihar, Penn State College of Medicine, Jamia Hamdard, Aligarh Muslim University
About
My research interests are in the area of immunology particularly on stem cells to treat immune mediated diseases. I am involved in the generation of immune cells mainly platelets, designer T cells and Treg cells from Hematopoietic stem cells (HSC), induced pluripotent stem (iPS) cells and Embryonic stem (ES) cells which can be used for adoptive immunotherapy and likely to contribute toward treatments of cancers, asthma, and autoimmune diseases.
For the first time we have reported that T lineage cells can be generated from iPS cells has been published in Cellular Immunology. This breakthrough research is very important for developing therapeutic immune cells since it provides a potential treatment target for patients.
My current ongoing research work revolving around identification of novel epitopes from Neoantigen/Antigen for the generation of novel epitope based vaccine for the treatment of Cancer and other diseases and dissecting the role of Telomerase complex and Notch signaling in the modulation of Cancer and Rheumatoid arthritis.
We have made significant contributions to the area of stem cell, lung biology, proteomics, immunomodulation and T cell based therapy, which is evident from our 60 peer reviewed full-length publication records in a variety of top class scientific journals and books.
Our research publications are cited by more than 3500 times by other research groups all over the world, which show high international recognition of our work and has very high impact with h-index 23 and i10-index 32
I have served as a Principle investigator in SERB funded grant and DST-FIST Level-1 as well as co-investigator in five major grants funded by American Society of Cancer and from several other organizations and has submitted two patents proposal based on iPS cells.
I have received several awards to travel Japan and California and was invited to present seminars at different universities in USA, India (and GE Healthcare, USA.
I was recognized as Best Postdoctoral Fellow in 2009 and ‘received several other awards from CSIR, CCRUM and Bharat Seva trust etc.
Employment
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Central University of South Bihar Professor2015 - Present
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Central University of South Bihar Associate Professor2012 - 2015
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Penn State College of Medicine Postdoctoral Fellow2003 - 2012
Education
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Jamia Hamdard M.Sc. (MS)1996 - 1998
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Aligarh Muslim University B.Sc. (BS)1993 - 1996
Projects & Funding
Projects & funding information is unavailable.
Publications (50)
- Colorectal Cancer (CRC): Investigating the Expression of the Suppressor of Fused (SuFu) Gene and Its Relationship with Several Inflammatory Blood-Based Biomarkers Save
- Cloning and functional characterization of arsenite oxidase (aoxB) gene associated with arsenic transformation in Pseudomonas sp. strain AK9 Save
- Transcriptional factors targeting in cancer stem cells for tumor modulation Save
- Insight into the transcription factors regulating Ischemic stroke and glioma in response to shared stimuli Save
- MCC950 Regulates Stem Cells Destiny Through Modulating SIRT3-NLRP3 Inflammasome Dynamics During Oxygen Glucose Deprivation Save
- Combinatorial Effect of Arsenic and Herbal Compounds in Telomerase-Mediated Apoptosis Induction in Liver Cancer Save
- Induction of Iron Stress in Hepatocellular Carcinoma Cell Lines by Siderophore of Aspergillus nidulans Towards Promising Anticancer Effect Save
- Truncated Human IRF-1 (1-233) protein shows neutral transcriptional effect on expression of Bax, survivin, Bcl2 and cyclin D1 genes in HEK293T cell line Save
- Analysis of mitochondrial DNA copy number variation in blood and tissue samples of metastatic breast cancer patients (A pilot study) Save
- The Healing Art of Arsenic in Various Malignancies Save