SG
Ganesan S
Weill Cornell Medicine, Research Institute of St. Louis, Hopital Saint Louis, Christian Medical College, Madurai Kamaraj University
Research areas: Medicine · Hematology · Acute Myeloid Leukemia Research · Retinoids in leukemia and cellular processes · Single-cell and spatial transcriptomics
Employment
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Weill Cornell Medicine Postdoctoral associate in medicine2021 - Present
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Research Institute of St. Louis, Hopital Saint Louis Post-doctoral fellow2019 - 2020
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Christian Medical College & Hospital Lecturer2018 - 2018
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Christian Medical College & Hospital Junior Research Fellow2010 - 2012
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Center for Stem Cell Research Junior Research Fellow2009 - 2010
Education
- 2012 - 2018
- 2007 - 2009
Projects & Funding
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Drug resistance in MPN Fondation de France
Publications (15)
- Single-cell mapping of regulatory DNA:Protein interactions Save
- Comprehensive analysis of mesenchymal cells reveals a dysregulated TGF-β/WNT/HOXB7 axis in patients with myelofibrosis Save
- Single-cell genotype-phenotype mapping identifies therapeutic vulnerabilities in VEXAS syndrome Save
- Metabolic adaptation drives arsenic trioxide resistance in acute promyelocytic leukemia Save
- A phase II study evaluating the role of bortezomib in the management of relapsed acute promyelocytic leukemia treated upfront with arsenic trioxide Save
- Combination lenalidomide/bortezomib treatment synergistically induces calpain-dependent Ikaros cleavage and apoptosis in myeloma cells Save
- Stromal cells downregulate miR-23a-5p to activate protective autophagy in acute myeloid leukemia Save
- T-Cell Protein Tyrosine Phosphatase Is Irreversibly Inhibited by Etoposide-Quinone, a Reactive Metabolite of the Chemotherapy Drug Etoposide Save
- Prevalence of FVIII inhibitors in severe haemophilia A patients: Effect of treatment and genetic factors in an Indian population. Save
- Arsenic Trioxide Enhances the NK Cell Cytotoxicity Against Acute Promyelocytic Leukemia While Simultaneously Inhibiting Its Bio-Genesis. Save
- Comprehensive mutational analysis of primary and relapse acute promyelocytic leukemia Save
- Rationale and efficacy of proteasome inhibitor combined with arsenic trioxide in the treatment of acute promyelocytic leukemia. Save
- pVAX14DNA-mediated add-on immunotherapy combined with arsenic trioxide and all-trans retinoic acid targeted therapy effectively increases the survival of acute promyelocytic leukemia mice. Save
- Comparison of newly diagnosed and relapsed patients with acute promyelocytic leukemia treated with arsenic trioxide: insight into mechanisms of resistance. Save
- Role of minimal residual disease monitoring in acute promyelocytic leukemia treated with arsenic trioxide in frontline therapy. Save