Niek de Lange

About

I am a scientist with a passion in the fields of Physical chemistry, biophysics, microfluidics and molecular biology. I have achieved both my bachelor and Master degree at the Wageningen university in the field of Molecular Life Sciences. I recently started as a PhD candidate at the Physical Chemistry and Soft Matter department of the Wageningen University.

I currently work on studying double bilayers, using different model membrane systems: A supported Double Lipid Bilayer (SDLB) and Attached Lipid Liposomes. I achieve the double bilayers through the use of various linker molecules, like Biotin and Streptavidin or telechelic associative polymers.

The combination of both model membrane systems allows me to assess the stability of biomembranes using techniques like AFM (Atomic Force Microscopy), DLS (Dynamic Light Scattering), Reflectometry and TIRF microscopy (Total Internal Reflection Fluorescence microscopy).

Employment

• Hogeschool Utrecht Instituut for Life Science en Chemie Hogeschooldocent
  2021 - Present
• Wageningen University and Research Centre PhD Candidate
  2016 - 2021

Education

• Wageningen Universiteit MSc Molecular Life Sciences
  2013 - 2016
• Wageningen Universiteit BSc Molecular Life Sciences
  2009 - 2013

Projects & Funding

Projects & funding information is unavailable.

Publications (8)

• Structural and mechanical parameters of lipid bilayer membranes using a lattice refined self-consistent field theory
  Physical Chemistry Chemical Physics 2021 DOI: 10.1039/d0cp05597b
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• Self-limiting aggregation of phospholipid vesicles
  Soft Matter 2020 DOI: 10.1039/c9sm01692a
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• Step-wise linking of vesicles by combining reversible and irreversible linkers – towards total control on vesicle aggregate sizes
  Soft Matter 2020 DOI: 10.1039/d0sm00995d
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• Unraveling the causes of adaptive benefits of synonymous mutations in TEM-1 β-lactamase
  Heredity 2018 DOI: 10.1038/s41437-018-0104-z
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• An acidic model pro-peptide affects the secondary structure, membrane interactions and antimicrobial activity of a crotalicidin fragment
  Scientific Reports 2018 DOI: 10.1038/s41598-018-29444-0
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• Electrical lysis of cells for detergent-free droplet assays
  Biomicrofluidics 2016 DOI: 10.1063/1.4944742
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• Temperature Controlled Sequential Gelation in Composite Microgel Suspensions
  Particle & Particle Systems Characterization 2015 DOI: 10.1002/ppsc.201500007
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• Compact and modular multicolour fluorescence detector for droplet microfluidics
  Lab on a Chip 2015 DOI: 10.1039/c5lc00333d
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