Scott Guimond

Employment

• Keele University Lecturer in Biosciences
  2018 - Present
• University of Liverpool Post-doctoral research fellow
  2003 - Present
• University of Birmingham Post-doctoral research fellow
  1997 - 2003

Education

Education history is unavailable.

Projects & Funding

Projects & funding information is unavailable.

Publications (44)

• High sensitivity (zeptomole) detection of BODIPY-labelled heparan sulfate (HS) disaccharides by ion-paired RP-HPLC and LIF detection enables analysis of HS from mosquito midguts
  Analytical Methods 2023 DOI: 10.1039/D2AY01803A
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• Glycosaminoglycans from Litopenaeus vannamei Inhibit the Alzheimer’s Disease β Secretase, BACE1
  Marine Drugs 2021 DOI: 10.3390/md19040203
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• The hyperlipidaemic drug fenofibrate significantly reduces infection by SARS-CoV-2 in cell culture models
  2021 DOI: 10.1101/2021.01.10.426114
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• Glycosaminoglycans induce conformational change in the SARS-CoV-2 Spike S1 Receptor Binding Domain
  2020 DOI: 10.1101/2020.04.29.068767
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• SARS-CoV-2 Spike S1 Receptor Binding Domain undergoes Conformational Change upon Interaction with Low Molecular Weight Heparins
  2020 DOI: 10.1101/2020.04.29.068486
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• Heparin inhibits cellular invasion by SARS-CoV-2: structural dependence of the interaction of the surface protein (spike) S1 receptor binding domain with heparin
  2020 DOI: 10.1101/2020.04.28.066761
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• The 2019 coronavirus (SARS-CoV-2) surface protein (Spike) S1 Receptor Binding Domain undergoes conformational change upon heparin binding
  2020 DOI: 10.1101/2020.02.29.971093
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• Tools for the Quality Control of Pharmaceutical Heparin
  Medicina 2019 DOI: 10.3390/medicina55100636
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• A Glycosaminoglycan Extract from Portunus pelagicus Inhibits BACE1, the β Secretase Implicated in Alzheimer’s Disease
  Marine Drugs 2019 DOI: 10.3390/md17050293
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• Heparan Sulfate Proteoglycan Synthesis Is Dysregulated in Human Osteoarthritic Cartilage
  The American Journal of Pathology 2019 DOI: 10.1016/j.ajpath.2018.11.011
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• Dendrimer Heparan Sulfate Glycomimetics: Potent Heparanase Inhibitors for Anticancer Therapy
  ACS Chemical Biology 2018 DOI: 10.1021/acschembio.8b00909
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• The potential for circular dichroism as an additional facile and sensitive method of monitoring low-molecular-weight heparins and heparinoids
  Thrombosis and Haemostasis 2017 DOI: 10.1160/th08-12-0797
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• A semi-synthetic glycosaminoglycan analogue inhibits and reverses Plasmodium falciparum cytoadherence
  PLOS ONE 2017 DOI: 10.1371/journal.pone.0186276
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• Versatile Separation and Analysis of Heparan Sulfate Oligosaccharides Using Graphitized Carbon Liquid Chromatography and Electrospray Mass Spectrometry
  Analytical Chemistry 2017 DOI: 10.1021/acs.analchem.7b01417
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• Dynamic changes in heparan sulfate during muscle differentiation and ageing regulate myoblast cell fate and FGF2 signalling
  Matrix Biology 2017 DOI: 10.1016/j.matbio.2016.07.007
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• Sulfatase-mediated manipulation of the astrocyte-Schwann cell interface
  Glia 2016 DOI: 10.1002/glia.23047
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• Sulf1 and Sulf2 Differentially Modulate Heparan Sulfate Proteoglycan Sulfation during Postnatal Cerebellum Development: Evidence for Neuroprotective and Neurite Outgrowth Promoting Functions
  PLOS ONE 2015 DOI: 10.1371/journal.pone.0139853
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• 2-O Heparan Sulfate Sulfation by Hs2st Is Required for Erk/Mapk Signalling Activation at the Mid-Gestational Mouse Telencephalic Midline
  PLOS ONE 2015 DOI: 10.1371/journal.pone.0130147
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• Distinct patterns of heparan sulphate in pancreatic islets suggest novel roles in paracrine islet regulation
  Molecular and Cellular Endocrinology 2015 DOI: 10.1016/j.mce.2014.09.011
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• Single-Entity Heparan Sulfate Glycomimetic Clusters for Therapeutic Applications
  Angewandte Chemie 2015 DOI: 10.1002/ange.201410251
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