Rajeev Kumar

About

Rajeev Kumar
Flat #401, B - Block, G.K.Lake View Apartment
Ananthpura, Yelahanka Hobli, Bangalore, Karnataka 560064
Phone: +91 9886292954
[email protected]
www.linkedin.com/in/rajeev-kumar-763b278


Highlights

13 years industry experience in the development and application of mechanistic models to address questions relevant to drug discovery and development.

• Developed fit-for-purpose models to support drug discovery programs
• Developed QSP models to aid in lead drug optimization
• Developed systems models to predict drug-induced liver injury (DILI)
• Contributed extensively to the development of an in-silico predictive platform for DILI prediction
• Developed PK-PD models for human dose projection and dosing regimen of a drug from pre-clinical data
• Developed PBPK models to understand the role of target in drug disposition
• Implemented PDE (partial differential equation) based model in MATLAB to predict drug-induced renal toxicity
• Implemented workflow to integrate OMICS data into a systems model
• Analyzed OMICS data for the pathway analysis and biomarker identification
• Worked extensively in the areas of drug-induced liver injury, Immunoscience, and liver fibrosis

Employment

• Cellworks Research India Pvt Ltd Senior lead scientist
  2021 - Present
• Biocon Bristol-Myers Squibb Research and Development Center Senior Research Scientist
  2016 - 2021
• Strand Life Sciences Senior Scientist
  2007 - 2016

Education

Education history is unavailable.

Projects & Funding

Projects & funding information is unavailable.

Publications (1)

• Evaluation of Coproporphyrins I and III as an Endogenous Marker for Hepatic Organic Anion Transporting Polypeptides and Multidrug Resistance-Associated Proteins (MRP 2/3) Activity in Animal Models of Nonalcoholic Steatohepatitis Using a Mechanistic Model
  2023 DOI: 10.20944/preprints202309.0208.v1
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