MM

Musa Marimani

University of the Witwatersrand, Johannesburg

Research areas: Medicine · Microbiology · Salmonella and Campylobacter epidemiology · Antibiotic Resistance in Bacteria · Tuberculosis Research and Epidemiology

ORCID iD 0000-0002-6007-586X
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About

Research Biosketch:
Dr. Marimani is a South African researcher currently serving as a lecturer in the Department of Anatomical Pathology at the University of the Witwatersrand Medical School in Johannesburg, South Africa. The incumbent is interested in investigating the role of epigenetic mechanisms in advancing tuberculosis (TB) and HIV infection. Certain epigenetic modifications such as methylation, phosphorylation and acetylation are introduced by HIV and Mycobacterium tuberculosis (Mtb) and subvert the host immunity leading to extensive microbial infection. The sub-Saharan African region possesses an increasing number of individuals co-infected with various susceptible and drug-resistant Mtb and HIV strains. As such, in this region HIV prevalence is intensified by the high TB infection rate resulting in a large number of patients presenting with HIV-TB co-infection. Accordingly, our research projects are aimed at exploring epigenetic modifications introduced by HIV and TB in human hosts following infection. Adequate understanding of these mechanisms may potentially be utilised as useful biomarkers for diagnostic tests and synthesis of new and effective therapeutics.

Wits webpage:
https://www.wits.ac.za/people/academic-a-z-listing/m/mar/musamarimani1witsacza/

Research ORCID:
https://orcid.org/0000-0002-6007-586X

Employment

  • University of the Witwatersrand, Johannesburg Researcher
    2020 - Present

Education

Education history is unavailable.

Projects & Funding

  • The role of epigenetic modifications in advancing microbial infection in TB-HIV patients National Research Foundation
    2022 - 2024
  • The role of epigenetic modifications in advancing microbial infection in TB-HIV patients Carnegie
    2021 - 2023
  • Identification of molecular mechanisms leading to reactivation of Mycobacterium tuberculosis from latent state Wits Faculty of Health Sciences Research Committee (FRC) scholarship
    2019 - 2019
  • Identification of molecular mechanisms leading to reactivation of Mycobacterium tuberculosis from latent state National Research Foundation (NRF) of South Africa
    2017 - 2020
  • Identification of molecular mechanisms leading to reactivation of Mycobacterium tuberculosis from latent state University Research Committee scholarship (URC)
    2017 - 2018
  • Inhibition of hepatitis B virus (HBV) replication using synthetic antiviral RNA interference (RNAi) activators Health and Welfare Sector Education and Training Authority of South Africa (HWSETA)
    2014 - 2016
  • Inhibition of hepatitis B virus (HBV) replication using synthetic antiviral RNA interference (RNAi) activators National Research Foundation (NRF) of South Africa
    2011 - 2015
  • Inhibition of hepatitis B virus (HBV) replication using synthetic antiviral RNA interference (RNAi) activators Poliomyelitis Research Foundation (PRF)
    2011 - 2013
  • Inhibition of hepatitis B virus (HBV) replication using synthetic antiviral RNA interference (RNAi) activators The Ernst and Ethel Eriksen Trust
    2011 - 2013
  • Infection process and expression of anti-fungal compounds in avocado fruit infected with Colletotrichum gloeosporioides and molecular identification of fungal pathogens of avocado Postgraduate Merit Award (PMA) of the University of the Witwatersrand
    2009 - 2010
  • Infection process and expression of anti-fungal compounds in avocado fruit infected with Colletotrichum gloeosporioides and molecular identification of fungal pathogens of avocado The Ernst and Ethel Eriksen Trust
    2009 - 2010
  • Infection process and expression of anti-fungal compounds in avocado fruit infected with Colletotrichum gloeosporioides and molecular identification of fungal pathogens of avocado Gauteng Department of Agriculture, Conservation and Environment (GDACE) Biotechnology Bursary
    2009 - 2010
  • Infection process and expression of anti-fungal compounds in avocado fruit infected with Colletotrichum gloeosporioides and molecular identification of fungal pathogens of avocado Bradlow Scholarship
    2009 - 2010
  • Infection process and expression of anti-fungal compounds in avocado fruit infected with Colletotrichum gloeosporioides and molecular identification of fungal pathogens of avocado National Research Foundation (NRF) of South Africa
    2008 - 2009
  • A preliminary analysis of the HIV-1 Subtype C integrase gene from Musina National Research Foundation (NRF) of South Africa
    2007 - 2007
  • A preliminary analysis of the HIV-1 Subtype C integrase gene from Musina The South African AIDS Vaccine Initiative (SAAVI)
    2007 - 2007

Publications (29)