Gloria Ceballos-Pérez

About

Most of my scientific career has been focused on the study on gene expression regulation, mainly at the post-transcriptional level, in both model organisms and mammalian cells, and the identification of chemical compounds and new molecular targets against Trypanosoma brucei parasite. I did my degree in Biology at the University of Granada. During my university studies, I was awarded with an Ícaro scholarship for developing an internship of 3 months in Puleva Biotech S.A. After, I did a master ‘s thesis in Immunology, where I develop my TFM under the direction of Professor Ignacio Molina, at the Institute of Biopathology and Regenerative Medicine, University of Granada. Here, I developed a lentiviral vector capable of rescuing cellular defects in fibroblast mutant for the ATM gene as a future gene therapy for patients with Ataxia-Telangiectasia disease. These data were published in the journal Frontiers in Immunology (IF: 4.716, Q2), of which I am co-author. After this stage, I joined at Professor Miguel Navarro`s lab at the Institute of Parasitology and Biomedicine López-Neyra, (IPBLN, CSIC, Granada) where I worked on the characterization of AMPK kinase and other factors involved in the development of the quiescence stage of the T. brucei parasite. The results were not only published in the journal Cell Reports (IF: 8.282, Q1) (of which I am co-author), but also made the cover of the journal. In addition, during these years, I collaborated with Northeastern University (Boston, USA) in the development of high-throughput screening assays of chemical compounds against the parasite. As a result, I am co-author of 8 scientific articles in journals such as PLOS Neglected Tropical Diseases (IF: 3.885, Q1) and Journal of Medicinal Chemistry (IF: 8.039, Q1). Subsequently, I was awarded with a Spanish Government Grant (FPI) to develop my Doctoral Thesis at Dr. Antonio M. Estévez ‘s lab (IPBLN, CSIC). My research focused on the characterization of a T. brucei RNA-binding protein involved in 5S ribosomal RNA maturation and in protein translation. As a result, I published an article as a first author in the journal Parasites & Vectors (IF: 3.2, Q1). In addition, during this period, I participated in the characterization of two other RNA-binding proteins which are important regulators of parasite gene expression (both papers were published in the prestigious journal Nucleic Acids Research (IF: 14.9, D1). After obtaining my Ph.D. degree with a grade of cum laude, recently, I have joined Dr. Sara R. Heras ‘lab at Genyo, a Centre for Genomic and Oncological Research at Granada. I have applied my previous knowledge in post-transcriptional regulation to identify novel miRNAs that control retrotransposons mobility as potential therapy for human tumors and the results have been reported at congresses to date. In addition, we are collaborating with Sara Macias-Ribela, Senior Research Fellow from University of Edinburgh, to understand the role of retrotransposon-derived RNAs during early development and disease. In summary, thanks to the work done during all these years, I have published 13 scientific articles, participated in several national and international congresses, and collaborated with several prestigious research groups around the world.

Employment

• University of Granada Researcher assistant
  2023 - 2024
• Consejo Superior de Investigaciones Científicas Phd student
  2017 - 2022
• Consejo Superior de Investigaciones Científicas Researcher assistant
  2015 - 2017

Education

Education history is unavailable.

Projects & Funding

Projects & funding information is unavailable.

Publications

Publications are unavailable.