KP
Kalyan Kumar Pasunooti
Johns Hopkins University School of Medicine, Nanyang Technological University
Research areas: Chemistry · Organic Chemistry · Chemical Synthesis and Analysis · Synthesis and biological activity · Click Chemistry and Applications
0000-0002-6039-0122
Employment
-
Johns Hopkins University School of Medicine Research Fellow2022 - 2027
Education
- 2007 - 2011
Projects & Funding
Projects & funding information is unavailable.
Publications (28)
- Design, Synthesis, Molecular Docking Study and Biological Evaluation of Novel γ-Carboline Derivatives of Latrepirdine (Dimebon) as Potent Anticancer Agents Save
- Design and Synthesis of Tetrazole- and Pyridine-Containing Itraconazole Analogs as Potent Angiogenesis Inhibitors Save
- Thienopyrimidinone Derivatives That Inhibit Bacterial tRNA (Guanine37-N1)-Methyltransferase (TrmD) by Restructuring the Active Site with a Tyrosine-Flipping Mechanism Save
- Novel Tetrazole-Containing Analogues of Itraconazole as Potent Antiangiogenic Agents with Reduced Cytochrome P450 3A4 Inhibition Save
- Structure-activity relationship study of itraconazole, a broad-range inhibitor of picornavirus replication that targets oxysterol-binding protein (OSBP) Save
- Total chemical and semisynthetic approaches for the preparation of ubiquitinated proteins and their applications Save
- Simultaneous Targeting of NPC1 and VDAC1 by Itraconazole Leads to Synergistic Inhibition of mTOR Signaling and Angiogenesis Save
- Thiazolidine-Masked alpha-Oxo Aldehyde Functionality for Peptide and Protein Modification Save
- 5-Methylisoxazole-3-carboxamide-Directed Palladium-Catalyzed gamma-C(sp(3))-H Acetoxylation and Application to the Synthesis of gamma-Mercapto Amino Acids for Native Chemical Ligation Save
- Auxiliary-Directed Pd-Catalyzed γ-C(sp3)-H Bond Activation of α-Aminobutanoic Acid Derivatives (vol 17, pg 6094, 2015) Save
- Divergence of Antiangiogenic Activity and Hepatotoxicity of Different Stereoisomers of Itraconazole Save
- Genetic incorporation of 1,2-aminothiol functionality for site-specific protein modification via thiazolidine formation Save
- N-Linked Glycosyl Auxiliary-Mediated Native Chemical Ligation on Aspartic Acid: Application towards N-Glycopeptide Synthesis Save
- Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells Save
- Auxiliary-Directed Pd-Catalyzed gamma-C(sp(3))-H Bond Activation of alpha-Aminobutanoic Acid Derivatives Save
- Adamantyl Derivative As a Potent Inhibitor of Plasmodium FK506 Binding Protein 35 Save
- Benzofuran-Based Estrogen Receptor alpha Modulators as Anti-Cancer Therapeutics: In Silico and Experimental Studies Save
- A microwave-assisted, copper-catalyzed three-component synthesis of dihydropyrimidinones under mild conditions Save
- Aryl/hetero-arylethyne bridged dyes: the effect of planar pi-bridge on the performance of dye-sensitized solar cells Save
- Facile synthesis and characterization of new polymerizable conjugated 2,5-di(selenophen-2-yl)pyrroles and 2,5-difuranylpyrroles Save